GPR52 - G protein-coupled receptor 52-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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9293 GPR52

基因描述

Type	Description
Definition	G protein-coupled receptor 52

研究结论

Date	Results	Publications
2020-03-21 11:25:00	high-resolution structures of human GPR52 in three states: a ligand-free state, a Gs-coupled self-activation state and a potential allosteric ligand-bound state	32076264
2016-02-06 11:35:00	Data show that G protein-coupled receptor 52 (Gpr52) modulates huntingtin protein (Htt) levels in the striatal cells in vitro and in vivo.	25738228

名称对应

Type	IDs
Gene	UniProtKB-ID: GPR52_HUMAN, F2YGU0_HUMAN UniprotKB: Q9Y2T5, F2YGU0 UniParc: UPI0000153A3C EMBL: BC069460, CH471067, HQ995526, BC067456, BC067460, AL022171, BC095532, BC067459, AF096784, BC067457, BC067458 Ensembl: ENSG00000203737 KO: hsa:9293
Nucleutide sequences	EMBL-CDS: AAH67456.1, AAH67459.1, AAH95532.1, AAH69460.1, AAD22409.1, AAH67458.1, AAH67460.1, AAH67457.1, ADZ31971.1, EAW90976.1 Gene_ORFName: hCG_1648322 Ensembl_TRS: ENST00000367685
Protein sequencees	Ensembl_PRO: ENSP00000356658 RefSeq: NP_005675.3
Others	UniRef100: UniRef100_Q9Y2T5 UniRef90: UniRef90_P0C5J4 UniRef50: UniRef50_P0C5J4 UniGene: Hs.673850 CCDS: CCDS30941.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32814053	Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker	2020-08-18	-
32076264	Structural basis of ligand recognition and self-activation of orphan GPR52. Nature Xi Lin , Mingyue Li , Niandong Wang , Yiran Wu , Zhipu Luo , Shimeng Guo , Gye-Won Han , Shaobai Li , Yang Yue , Xiaohu Wei , Xin Xie , Yong Chen , Suwen Zhao , Jian Wu , Ming Lei , Fei Xu	2020-03-01	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-
25738228	A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. Elife Yuwei Yao , Xiaotian Cui , Ismael Al-Ramahi , Xiaoli Sun , Bo Li , Jiapeng Hou , Marian Difiglia , James Palacino , Zhi-Ying Wu , Lixiang Ma , Juan Botas , Boxun Lu	2015-01-01	Htt, Gpr52, GPR52
24587241	Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders. PLoS ONE Hidetoshi Komatsu , Minoru Maruyama , Shuuhei Yao , Tokuyuki Shinohara , Kensuke Sakuma , Sachiko Imaichi , Tomoko Chikatsu , Kanako Kuniyeda , Foo Kok Siu , Lam Sock Peng , Katherine Zhuo , Lay Sock Mun , Tan Min Han , Yoshio Matsumoto , Tadatoshi Hashimoto , Nobuyuki Miyajima , Yasuaki Itoh , Kazuhiro Ogi , Yugo Habata , Masaaki Mori	2014-01-01	-
23333304	CBFÎ² stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Mol Cell Dong Young Kim , Eunju Kwon , Paul D Hartley , David C Crosby , Sumanjit Mann , Nevan J Krogan , John D Gross	2013-02-21	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21044950	Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. Mol Cell Proteomics Ok-Hee Lee , Hyeung Kim , Quanyuan He , Hwa Jin Baek , Dong Yang , Liuh-Yow Chen , Jiancong Liang , Heekyung Kate Chae , Amin Safari , Dan Liu , Zhou Songyang	2011-02-01	-
16710414	The DNA sequence and biological annotation of human chromosome 1. Nature S G Gregory , K F Barlow , K E McLay , R Kaul , D Swarbreck , A Dunham , C E Scott , K L Howe , K Woodfine , C C A Spencer , M C Jones , C Gillson , S Searle , Y Zhou , F Kokocinski , L McDonald , R Evans , K Phillips , A Atkinson , R Cooper , C Jones , R E Hall , T D Andrews , C Lloyd , R Ainscough , J P Almeida , K D Ambrose , F Anderson , R W Andrew , R I S Ashwell , K Aubin , A K Babbage , C L Bagguley , J Bailey , H Beasley , G Bethel , C P Bird , S Bray-Allen , J Y Brown , A J Brown , D Buckley , J Burton , J Bye , C Carder , J C Chapman , S Y Clark , G Clarke , C Clee , V Cobley , R E Collier , N Corby , G J Coville , J Davies , R Deadman , M Dunn , M Earthrowl , A G Ellington , H Errington , A Frankish , J Frankland , L French , P Garner , J Garnett , L Gay , M R J Ghori , R Gibson , L M Gilby , W Gillett , R J Glithero , D V Grafham , C Griffiths , S Griffiths-Jones , R Grocock , S Hammond , E S I Harrison , E Hart , E Haugen , P D Heath , S Holmes , K Holt , P J Howden , A R Hunt , S E Hunt , G Hunter , J Isherwood , R James , C Johnson , D Johnson , A Joy , M Kay , J K Kershaw , M Kibukawa , A M Kimberley , A King , A J Knights , H Lad , G Laird , S Lawlor , D A Leongamornlert , D M Lloyd , J Loveland , J Lovell , M J Lush , R Lyne , S Martin , M Mashreghi-Mohammadi , L Matthews , N S W Matthews , S McLaren , S Milne , S Mistry , M J F Moore , T Nickerson , C N O'Dell , K Oliver , A Palmeiri , S A Palmer , A Parker , D Patel , A V Pearce , A I Peck , S Pelan , K Phelps , B J Phillimore , R Plumb , J Rajan , C Raymond , G Rouse , C Saenphimmachak , H K Sehra , E Sheridan , R Shownkeen , S Sims , C D Skuce , M Smith , C Steward , S Subramanian , N Sycamore , A Tracey , A Tromans , Z Van Helmond , M Wall , J M Wallis , S White , S L Whitehead , J E Wilkinson , D L Willey , H Williams , L Wilming , P W Wray , Z Wu , A Coulson , M Vaudin , J E Sulston , R Durbin , T Hubbard , R Wooster , I Dunham , N P Carter , G McVean , M T Ross , J Harrow , M V Olson , S Beck , J Rogers , D R Bentley , R Banerjee , S P Bryant , D C Burford , W D H Burrill , S M Clegg , P Dhami , O Dovey , L M Faulkner , S M Gribble , C F Langford , R D Pandian , K M Porter , E Prigmore	2006-05-18	-

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