| Type | Description |
|---|---|
| Definition | BPI fold containing family B member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 11:16:00 | BPIFB1 negatively regulates its interactor VTN, thereby inhibiting VTN-induced proliferation, antiapoptotic effects, G2/M phase arrest, DSB repair, and the activation of the ATM-Chk2 and ATR-Chk1 pathways after irradiation. | 29568064 |
| 2019-12-21 12:01:00 | A novel mechanism underlying the anticancer effect of LPLUNC1 and clarifying that PHB1 may represent a novel, promising candidate tumour suppressor gene in Nasopharyngeal carcinoma, with potential therapeutic target value. | 30886235 |
| 2019-01-19 11:42:00 | Results showed that BPIFB1 expression markedly inhibited NPC cell migration, invasion, and lung-metastatic abilities. Additionally, identification of two BPIFB1-interacting proteins, VTN and VIM, showed that BPIFB1 reduced VTN expression and the formation of a VTN-integrin alphaV complex in NPC cells, leading to inhibition of the FAK/Src/ERK signalling pathway. | 29123267 |
| 2018-09-22 10:59:00 | BPIFA1 and BPIFB1 expressions are correlated with goblet cell metaplasia and inversely correlated with lung function parameters of airway obstruction (FEV1 and FEV1/FVC) in COPD patients. | 29296079 |
| 2016-02-06 10:09:00 | The G allele of rs1078761 may be detrimental to lung function in cystic fibrosis owing to decreased levels of BPIFA1 and BPIFB1. | 25574903 |
| Type | IDs |
|---|---|
| Synonymous | C20orf114, LPLUNC1 |
| Gene |
UniProtKB-ID:
BPIB1_HUMAN
UniprotKB:
Q8TDL5
UniParc:
UPI000006EEF9,
UPI00001C0F10
EMBL:
AL355392,
AY358595,
AL121901,
BC008429,
AK290243,
AF364078,
AK127971
Ensembl:
ENSG00000125999
KO:
hsa:92747
|
| Nucleutide sequences |
EMBL-CDS:
BAC87212.1,
AAH08429.1,
AAQ88958.1,
AAM00283.1,
BAF82932.1
Gene_ORFName:
UNQ706/PRO1357
Ensembl_TRS:
ENST00000253354
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253354
RefSeq:
NP_149974.2,
XP_024307786.1
|
| Others |
UniRef100:
UniRef100_Q8TDL5
UniRef90:
UniRef90_Q8TDL5
UniRef50:
UniRef50_Q8TDL5
UniGene:
Hs.65551
CCDS:
CCDS13218.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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