| Type | Description |
|---|---|
| Definition | integrin subunit beta 1 binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:00:00 | Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation. | 32005669 |
| 2017-08-05 11:57:00 | ICAP-1 monoubiquitylation helps in switching from ROCK2-mediated to MRCKalpha-mediated cell contractility. | 28049720 |
| 2017-06-03 12:19:00 | nuclear-cytoplasmic shuttling of ICAP1 influences both integrin activation and KRIT1 localization, presumably impacting nuclear functions of KRIT1. | 28003363 |
| 2014-02-08 10:36:00 | The cocrystal structure of ICAP1 in complex with krev interaction trapped protein (KRIT)1 is characterized here. | 23695561 |
| 2013-04-20 12:01:00 | The structural basis for KRIT1 antagonized ICAP1-modulated integrin-beta1 activation. | 23317506 |
| Type | IDs |
|---|---|
| Synonymous | ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B |
| Gene |
UniProtKB-ID:
ITBP1_HUMAN,
B4DQY5_HUMAN
UniprotKB:
O14713,
B4DQY5
UniParc:
UPI000012DA43,
UPI000002AC4E,
UPI0000208E1E
EMBL:
AK299017,
AC080162,
AF012024,
CH471053,
BC012264,
AF012023
Ensembl:
ENSG00000119185
KO:
hsa:9270
|
| Nucleutide sequences |
EMBL-CDS:
EAX00997.1,
EAX00992.1,
EAX01001.1,
AAB88671.1,
AAY14857.1,
EAX00993.1,
EAX00995.1,
AAB88672.1,
EAX01000.1,
AAH12264.1,
BAG61097.1
Ensembl_TRS:
ENST00000360635,
ENST00000238091,
ENST00000488451,
ENST00000355346
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000419524,
ENSP00000238091,
ENSP00000347504,
ENSP00000353850
RefSeq:
NP_001305996.1,
NP_071729.1,
NP_001305999.1,
NP_004754.1,
XP_006711966.1,
XP_016860756.1,
NP_001305998.1,
NP_001356677.1,
NP_001356674.1,
NP_001356675.1,
NP_001305997.1,
NP_001356679.1,
NP_001356673.1,
NP_001356678.1,
NP_001305995.1,
NP_001356676.1,
XP_016860759.1
|
| Others |
UniRef100:
UniRef100_O14713,
UniRef100_B4DQY5
UniRef90:
UniRef90_O14713,
UniRef90_F7IB20
UniRef50:
UniRef50_F7IB20,
UniRef50_O14713
UniGene:
Hs.467662
CCDS:
CCDS1662.1,
CCDS1663.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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