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9267 CYTH1

9267

CYTH1

cytohesin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition cytohesin 1

研究结论

Date Results Publications
2020-01-11 10:41:00 GBF1 alone maintains Golgi architecture; facilitates secretion; activates ADP-ribosylation factor (ARF)1, 3, 4, and 5; and recruits ARF effectors to Golgi membranes. 30943106
2019-10-26 10:26:00 HGF-induced migration depends on the phosphatidylinositol 3,4,5-triphosphate-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1. 30404949
2018-07-14 11:24:00 computational study suggests that although curcumin to some extent binds with Tp receptor, yet the inhibition of Arf6GDP to Arf6GTP conversion appeared to be an important mechanism by which curcumin inhibits U46619-induced increase in PLD activity in PASMCs. 28780751
2017-08-19 11:08:00 CYTH1 is a novel major regulator of adhesion and engraftment in human hematopoietic stem and progenitor cells through mechanisms that, at least in part, involve the activation of integrins. 27899358
2017-08-05 12:27:00 FRMD4A or inhibition of cytohesins strongly upregulated secretion of endogenous tau. These results suggest that FRMD4A, a genetic risk factor for late-onset Alzheimer's disease, regulates tau secretion by activating cytohesin-Arf6 signaling. 27044754

名称对应

Type IDs
Synonymous B2-1, CYTOHESIN-1, D17S811E, PSCD1, SEC7
Gene
UniProtKB-ID: CYH1_HUMAN, B7Z9W0_HUMAN
UniprotKB: Q15438, B7Z9W0
UniParc: UPI0000D9E526, UPI000002A79D, UPI000000009A, UPI00019153A5
EMBL: AC099804, AF125352, AF125362, AF125354, AK293894, AK316277, BC050452, AC022966, M85169, AF125357, AF125355, AF125356, AK316075, AF125351, AF125353, AF125358, BC038385, AF125361, AF125350, AF125359, AF125360
Ensembl: ENSG00000108669
KO: hsa:9267
Nucleutide sequences
EMBL-CDS: AAA36602.1, AAF37738.1, BAH11620.1, BAH14648.1, AAH38385.1, AAF37737.1, AAH50452.1, BAH14446.1
Ensembl_TRS: ENST00000446868, ENST00000361101, ENST00000589297, ENST00000585509, ENST00000591455
Protein sequencees
Ensembl_PRO: ENSP00000465665, ENSP00000466512, ENSP00000389095, ENSP00000465940, ENSP00000354398
RefSeq: XP_011523779.1, NP_001351970.1, NP_001278948.1, NP_001351969.1, XP_011523780.1, XP_024306798.1, NP_004753.1, NP_001278947.1, XP_011523777.1, NP_001351967.1, NP_059430.2, NP_001351968.1, NP_001351966.1, XP_011523778.1
Others
UniRef100: UniRef100_B7Z9W0, UniRef100_Q15438
UniRef90: UniRef90_Q15438, UniRef90_B7Z9W0
UniRef50: UniRef50_Q6PC26, UniRef50_O43739
UniGene: Hs.191215
CCDS: CCDS42392.3, CCDS86644.1, CCDS32754.1

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