| Type | Description |
|---|---|
| Definition | translocase of inner mitochondrial membrane 50 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma. | 32810522 |
| 2020-03-14 12:31:00 | TIMM50 deficiency causes a severe mitochondrial dysfunction by targeting key aspects of mitochondrial physiology, such as the maintenance of proper mitochondrial morphology, OXPHOS assembly, and mitochondrial respiratory capacity. | 31058414 |
| 2019-10-26 12:07:00 | Amino acid changes that suppress the association of Tim50 with side-chain cleavage enzyme ablate metabolic activity. | 30348838 |
| 2019-07-06 12:13:00 | High TIMM50 expression is associated with non-small cell lung cancer progression. | 30604908 |
| 2019-06-01 12:33:00 | These results indicate that mutations in TIMM50 cause multiple mitochondrial bioenergetic dysfunction and that functional TIMM50 is essential for cell survival in OxPhos-dependent conditions. | 30190335 |
| Type | IDs |
|---|---|
| Synonymous | MGCA9, TIM50, TIM50L |
| Gene |
UniProtKB-ID:
TIM50_HUMAN,
A0A024R0M6_HUMAN
UniprotKB:
Q3ZCQ8,
A0A024R0M6
UniParc:
UPI0000161278,
UPI0000202335,
UPI00005DB2E5
EMBL:
AF130109,
BC121146,
CH471126,
AY551341,
BC009072,
AY444561,
BC010736,
BC050082,
AC011500
Ensembl:
ENSG00000105197
KO:
hsa:92609
|
| Nucleutide sequences |
EMBL-CDS:
AAS68537.1,
AAG35534.1,
AAT01208.1,
AAH10736.1,
AAH09072.1,
AAH50082.1,
AAI21147.1,
EAW56902.1,
EAW56903.1
Gene_ORFName:
PRO1512,
hCG_1996416
Ensembl_TRS:
ENST00000607714,
ENST00000544017
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000445806,
ENSP00000475531
RefSeq:
NP_001316488.1,
NP_001001563.2,
XP_011525793.1
|
| Others |
UniRef100:
UniRef100_Q3ZCQ8
UniRef90:
UniRef90_Q3ZCQ8
UniRef50:
UniRef50_Q3ZCQ8
UniGene:
Hs.590956,
Hs.597106
CCDS:
CCDS33023.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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