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925 CD8A

925

CD8A

CD8a molecule

protein-coding

Homo sapiens

基因描述

Type Description
Definition CD8a molecule

研究结论

Date Results Publications
2020-06-06 12:45:00 Although, there is no significant difference in the ratio of CD4 to CD8 between two groups, the expression level of CD8 in COVID-19 patients was significantly higher than the normal individuals. This result suggested that the cellular immune responses triggered by COVID-19 infection were developed through overexpression of CD8 and hyperactivation of cytotoxic T lymphocytes. 32325421
2020-04-25 12:24:00 Not satisfying the Yonsei criteria (p=0.021), having >/= two metastatic LNs (p=0.032), low levels of tumor infiltrating CD8 T-cells (p=0.040) and a high Foxp3/CD8 ratio (p=0.032) were associated with unfavorable overall survival. 32233171
2020-04-25 10:49:00 an increased content of CD8 and a decreased CD4/CD8 ratio are each favorable prognosis markers in IgG nonresponders treated with a personalized peptide vaccination. 32058620
2020-01-11 10:41:00 High intraepithelial CD8 expression in the grade 3 endometrial carcinomas. 31197557
2019-09-14 10:29:00 CD8 represents both a prognostic and predictive factor of outcomes, while PD-L1 share different prognostic and predictive roles. 30318514

名称对应

Type IDs
Synonymous CD8, Leu2, p32
Gene
UniProtKB-ID: CD8A_HUMAN, Q8TAW8_HUMAN, Q6ZVS2_HUMAN
UniprotKB: P01732, Q8TAW8, Q6ZVS2
UniParc: UPI00000715E0, UPI00000726AA, UPI00001273B4, UPI00001C099A, UPI0000E5A272
EMBL: CH471053, M26313, M26315, M26314, AC064848, AK124156, BC025715, AC112696, AK300089, M27161, M12824, M12828
Ensembl: ENSG00000153563
KO: hsa:925
Nucleutide sequences
EMBL-CDS: AAA79218.1, EAW99440.1, EAW99439.1, AAA61133.1, EAW99438.1, AAX88864.1, AAA79217.1, AAA59674.1, AAB04637.1, BAG61892.1, AAH25715.1, BAC85789.1
Ensembl_TRS: ENST00000283635, ENST00000352580, ENST00000409511
Protein sequencees
Ensembl_PRO: ENSP00000386559, ENSP00000283635, ENSP00000321631
RefSeq: NP_001759.3, NP_741969.1, NP_001369627.1, NP_001139345.1
Others
UniRef100: UniRef100_Q8TAW8, UniRef100_P01732
UniRef90: UniRef90_A0A2I2ZXG0, UniRef90_P01732
UniRef50: UniRef50_P01732
UniGene: Hs.85258
CCDS: CCDS1992.1, CCDS1993.1

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