Type | Description |
---|---|
Definition | glucosaminyl (N-acetyl) transferase 3, mucin type |
Date | Results | Publications |
---|---|---|
2021-03-20 13:25:00 | Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis. | 32203219 |
2019-01-19 12:19:00 | High GCNT3 expression is associated with metastatic melanomas. | 28923134 |
2018-11-10 12:01:00 | GCNT3 was regarded as an oncogene in non-small cell lung cancer, and a target of miR-302b-3p, which regulated cell proliferation, migration and invasion in a GCNT3-dependent manner and E-cadherin, N-cadherin, vimentin, cyclin D1 and p-Erk appeared to be downstream molecules of the miR-302b-3p/GCNT3 pathway. | 30355927 |
2018-02-10 11:56:00 | In this Molecular Pathways article, we briefly discuss the potential role of mucin synthesis in cancers, ways to improve drug delivery and disrupt mucin mesh to overcome chemoresistance by targeting mucin synthesis, and the unique opportunity to target the GCNT3 pathway for the prevention and treatment of cancers. | 28039261 |
2015-08-29 10:42:00 | This study provides the concepts toward the design of carbohydrate-dependent inhibition of EPEC and EHEC O157:H7 adhesion to human intestinal epithelial cells. | 25701318 |
Type | IDs |
---|---|
Synonymous | C2/4GnT, C24GNT, C2GNT2, C2GNTM, GNTM |
Gene |
UniProtKB-ID:
GCNT3_HUMAN,
A0A024R5T9_HUMAN
UniprotKB:
O95395,
A0A024R5T9
UniParc:
UPI0000034962
EMBL:
BC017032,
CH471082,
EF152283,
AF038650,
AF102542
Ensembl:
ENSG00000140297
KO:
hsa:9245
|
Nucleutide sequences |
EMBL-CDS:
ABM21534.1,
AAH17032.1,
AAD10824.1,
AAD21525.1,
EAW77571.1,
EAW77572.1
Gene_ORFName:
hCG_32377
Ensembl_TRS:
ENST00000396065,
ENST00000560585
|
Protein sequencees |
Ensembl_PRO:
ENSP00000452741,
ENSP00000379377
RefSeq:
NP_004742.1
|
Others |
UniRef100:
UniRef100_O95395
UniRef90:
UniRef90_O95395
UniRef50:
UniRef50_O95395
UniGene:
Hs.194710
CCDS:
CCDS10172.1
|
排名 | 科研单位 | 文献 |
---|---|---|
1 |
University of Nebraska Medical Center |
2 |
2 |
Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA. |
1 |
3 |
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA. |
1 |
4 |
The Institute of Medical Science |
1 |
5 |
Beijing Institute of Radiation Medicine |
1 |
排名 | 研究人员 | 文献 |
---|---|---|
1 |
Pi-Wan Cheng |
5 |
2 |
Armen Petrosyan |
3 |
3 |
Mohamed F Ali |
2 |
4 |
Lily Ting |
1 |
5 |
Joao A Paulo |
1 |