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9245 GCNT3

9245

GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

protein-coding

Homo sapiens

基因描述

Type Description
Definition glucosaminyl (N-acetyl) transferase 3, mucin type

研究结论

Date Results Publications
2021-03-20 13:25:00 Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis. 32203219
2019-01-19 12:19:00 High GCNT3 expression is associated with metastatic melanomas. 28923134
2018-11-10 12:01:00 GCNT3 was regarded as an oncogene in non-small cell lung cancer, and a target of miR-302b-3p, which regulated cell proliferation, migration and invasion in a GCNT3-dependent manner and E-cadherin, N-cadherin, vimentin, cyclin D1 and p-Erk appeared to be downstream molecules of the miR-302b-3p/GCNT3 pathway. 30355927
2018-02-10 11:56:00 In this Molecular Pathways article, we briefly discuss the potential role of mucin synthesis in cancers, ways to improve drug delivery and disrupt mucin mesh to overcome chemoresistance by targeting mucin synthesis, and the unique opportunity to target the GCNT3 pathway for the prevention and treatment of cancers. 28039261
2015-08-29 10:42:00 This study provides the concepts toward the design of carbohydrate-dependent inhibition of EPEC and EHEC O157:H7 adhesion to human intestinal epithelial cells. 25701318

名称对应

Type IDs
Synonymous C2/4GnT, C24GNT, C2GNT2, C2GNTM, GNTM
Gene
UniProtKB-ID: GCNT3_HUMAN, A0A024R5T9_HUMAN
UniprotKB: O95395, A0A024R5T9
UniParc: UPI0000034962
EMBL: BC017032, CH471082, EF152283, AF038650, AF102542
Ensembl: ENSG00000140297
KO: hsa:9245
Nucleutide sequences
EMBL-CDS: ABM21534.1, AAH17032.1, AAD10824.1, AAD21525.1, EAW77571.1, EAW77572.1
Gene_ORFName: hCG_32377
Ensembl_TRS: ENST00000396065, ENST00000560585
Protein sequencees
Ensembl_PRO: ENSP00000452741, ENSP00000379377
RefSeq: NP_004742.1
Others
UniRef100: UniRef100_O95395
UniRef90: UniRef90_O95395
UniRef50: UniRef50_O95395
UniGene: Hs.194710
CCDS: CCDS10172.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of Nebraska Medical Center

2
2

Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA.

1
3

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

1
4

The Institute of Medical Science

1
5

Beijing Institute of Radiation Medicine

1
热点人员
排名 研究人员 文献
1

Pi-Wan Cheng

5
2

Armen Petrosyan

3
3

Mohamed F Ali

2
4

Lily Ting

1
5

Joao A Paulo

1
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