Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

Nat Metab     Michael Aregger , Keith A Lawson , Maximillian Billmann , Michael Costanzo , Amy H Y Tong , Katherine Chan , Mahfuzur Rahman , Kevin R Brown , Catherine Ross , Matej Usaj , Lucy Nedyalkova , Olga Sizova , Andrea Habsid , Judy Pawling , Zhen-Yuan Lin , Hala Abdouni , Cassandra J Wong , Alexander Weiss , Patricia Mero , James W Dennis , Anne-Claude Gingras , Chad L Myers , Brenda J Andrews , Charles Boone , Jason Moffat

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Cell     Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi

Image-based genome-wide siRNA screen identifies selective autophagy factors.

Nature     Anthony Orvedahl , Rhea Sumpter , Guanghua Xiao , Aylwin Ng , Zhongju Zou , Yi Tang , Masahiro Narimatsu , Christopher Gilpin , Qihua Sun , Michael Roth , Christian V Forst , Jeffrey L Wrana , Ying E Zhang , Katherine Luby-Phelps , Ramnik J Xavier , Yang Xie , Beth Levine

Toward an understanding of the protein interaction network of the human liver.

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Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

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Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

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Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

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