| Type | Description |
|---|---|
| Definition | transforming growth factor beta regulator 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | TBRG4 silencing promotes progression of squamous cell carcinoma via regulation of CAV-1 expression and formation. | 32415943 |
| 2017-12-02 11:10:00 | Despite the fact that proteins of the FASTK family FASTKD1-5 share the same domains, they exhibit various-sometimes opposing-functions in almost all steps of mitochondrial RNA metabolism. | 29036396 |
| 2017-10-07 12:53:00 | Disruption of FASTKD4 reduces the level of ND3 and of other mature mRNAs including ND5 and CYB, and causes accumulation of ND5-CYB precursor RNA. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone, indicating that FASTKD4 loss is epistatic. RAP domain of FASTKD4 has a nuclease fold with a conserved aspartate at the putative active site, mutation of which abolishes its function. | 28335001 |
| 2017-07-08 11:51:00 | SLERT is 694 nucleotides & contains SNORA5A & SNORA5C at its ends; it is produced from the human TBRG4 locus via skipping of exons 4 and 5 that leads to both SNORA5A & SNORA5C embedded within one intron, thereby producing SLERT from this alternatively spliced intron; results reveal an important control of ribosome biogenesis by SLERT lncRNA & its regulatory role in DDX21 ring-shaped arrangements acting on Pol I complexes. | 28475895 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| Type | IDs |
|---|---|
| Synonymous | CPR2, FASTKD4 |
| Gene |
UniProtKB-ID:
FAKD4_HUMAN,
B4DU42_HUMAN,
B3KRS4_HUMAN,
B3KM73_HUMAN
UniprotKB:
Q969Z0,
B4DU42,
B3KRS4,
B3KM73
UniParc:
UPI000015F305,
UPI000006ED7F,
UPI00017A7D08,
UPI0000071F89,
UPI000006F717
EMBL:
AF011792,
AK092132,
AK298155,
AK300489,
AB023165,
CH236960,
BC002732,
AL833840,
CH471128,
AK001281,
BC014918,
BC017235,
AK222943
Ensembl:
ENSG00000136270
KO:
hsa:9238
|
| Nucleutide sequences |
EMBL-CDS:
CAD38700.1,
EAL23745.1,
AAH14918.1,
AAH17235.1,
EAW61052.1,
BAA76792.2,
AAH02732.2,
EAL23744.1,
EAW61054.1,
EAW61051.1,
AAB69312.1,
EAW61055.1,
BAD96663.1,
BAG62204.1,
BAG52486.1,
BAH12734.1,
BAG50885.1
Ensembl_TRS:
ENST00000258770,
ENST00000361278,
ENST00000494076,
ENST00000395655
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258770,
ENSP00000420597,
ENSP00000379016,
ENSP00000354992
RefSeq:
NP_004740.2,
NP_001248763.1,
NP_112162.1,
NP_954573.1
|
| Others |
UniRef100:
UniRef100_Q969Z0,
UniRef100_Q969Z0-2
UniRef90:
UniRef90_Q969Z0-2,
UniRef90_Q969Z0
UniRef50:
UniRef50_Q969Z0
UniGene:
Hs.231411,
Hs.741611
CCDS:
CCDS5501.1,
CCDS5502.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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