| Type | Description |
|---|---|
| Definition | crumbs cell polarity complex component 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:47:00 | Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer. | 31087799 |
| 2020-07-04 10:24:00 | The Crb3 may promote colon cancer cell migration by regulating the expression of GSLs on the cell surface. | 31500807 |
| 2020-06-20 12:03:00 | Knockout (KO) of apical polarity determinant Crumbs 3 (Crb3) enhances Adeno-associated viruses (AAV) transduction, while overexpression exerts the opposite effect. Crb3 restricts AAV transduction in a serotype- and cell type-specific manner. Increased availability of galactosylated glycans on the surfaces of Crb3 KO cells, but not the universal AAV receptor, leads to increased capsid attachment and enhanced transduction. | 31391273 |
| 2020-02-22 12:09:00 | CRB3 strongly promotes tumor invasion and metastasis of human colon adenocarcinoma cells. Correlative expression between CRB3 and FGFR1 was consistently detected in primary and metastatic colorectal cancer patient tissues. Taking these together, CRB3 critically accelerates cell migration, namely invasion and metastasis of human colon cancers, through specific interaction to FGFR1 on colon cancer cells. | 30980524 |
| 2020-02-15 12:38:00 | CRB3 DNA methylation negatively correlated with CRB3 mRNA expression. CRB3 DNA methylation was also related to pathologic stage, T stage, N stage, and M stage of ccRCC. | 31147860 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CRUM3_HUMAN
UniprotKB:
Q9BUF7
UniParc:
UPI00000389E7,
UPI000004EE8D
EMBL:
AY103469,
AF503290,
AY358684,
CH471139,
BC002652,
BC018409,
AK292956
Ensembl:
ENSG00000130545
KO:
hsa:92359
|
| Nucleutide sequences |
EMBL-CDS:
EAW69084.1,
AAM44074.1,
AAM23013.1,
AAH02652.2,
EAW69085.1,
AAH18409.1,
EAW69086.1,
BAF85645.1,
AAQ89047.1
Gene_ORFName:
UNQ588/PRO1158
Ensembl_TRS:
ENST00000598494,
ENST00000600229,
ENST00000308243,
ENST00000356762
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310123,
ENSP00000469707,
ENSP00000472010,
ENSP00000349204
RefSeq:
NP_631900.1,
XP_016882960.1,
NP_777377.1,
NP_777378.1
|
| Others |
UniRef100:
UniRef100_Q9BUF7
UniRef90:
UniRef90_Q9BUF7
UniRef50:
UniRef50_Q9BUF7
UniGene:
Hs.150319
CCDS:
CCDS12167.1,
CCDS12166.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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