| Type | Description |
|---|---|
| Definition | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 13:08:00 | MAGI1 was markedly decreased in the Renal cell carcinoma (RCC) and indicated poor survival. Furthermore, we found that MAGI1 suppressed the invasion and migration of human RCC cells. Mechanistic investigations revealed that MAGI1 stabilized the PTEN/MAGI1/beta-catenin complex to inhibit beta-catenin signaling pathway. Moreover, MAGI1 was targeted by miR-520h which was transcriptionally activated by c-Myb. | 31352641 |
| 2020-01-04 11:41:00 | The authors report MAGI1 as a novel fluid shear stress-induced transcript/protein in endothelial cells that regulates eNOS (endothelial nitric oxide synthase) phosphorylation and nitric oxide production through phosphorylation. | 31035633 |
| 2018-06-30 10:39:00 | Decreased MAGI1 expression in the colonic mucosa might contribute to the pathogenesis of microscopic colitis. | 29204743 |
| 2018-06-23 11:06:00 | it negatively controls the cell growth of various types of cells and positively controls cell-cell interaction and the decreased expression of MAGI-1 in human T cells contributes to the development of several types of T-cell leukemia, partly through the stimulation of the Akt and MEK pathways. | 29043551 |
| 2017-08-26 12:47:00 | Study presented a combined molecular dynamics/infrared spectroscopy approach to the study of ligand binding (11-residue peptide derived from the C terminus of HPV16 E6) by the PDZ1 domain of MAGI1, focusing in particular on the far-infrared region of the spectrum. | 28636914 |
| Type | IDs |
|---|---|
| Synonymous | AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, MAGI-1b, Magi1d, TNRC19, WWP3 |
| Gene |
UniProtKB-ID:
MAGI1_HUMAN
UniprotKB:
Q96QZ7
UniParc:
UPI0001BE80D2,
UPI0000457133,
UPI0000457134,
UPI0000457132,
UPI0000D61B26,
UPI0001BE80D3,
UPI00005B2E0B
EMBL:
AC104438,
AK289803,
U80754,
AF401655,
AC112516,
U96115,
AF401654,
AF401656,
AB010894,
AC121493,
AC145425
Ensembl:
ENSG00000151276,
ENSG00000282956
KO:
hsa:9223
|
| Nucleutide sequences |
EMBL-CDS:
AAK94066.1,
BAA32002.1,
AAC04844.1,
AAK94065.1,
AAC51326.1,
BAF82492.1,
AAK94064.1
Ensembl_TRS:
ENST00000635378,
ENST00000634409,
ENST00000402939,
ENST00000483466,
ENST00000635471,
ENST00000497477,
ENST00000634774,
ENST00000330909
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385450,
ENSP00000420323,
ENSP00000489322,
ENSP00000489393,
ENSP00000424369,
ENSP00000331157,
ENSP00000489444,
ENSP00000489391
RefSeq:
NP_001352834.1,
NP_056335.1,
NP_001352832.1,
NP_001028229.1,
NP_004733.2,
NP_001352833.1
|
| Others |
UniRef100:
UniRef100_Q96QZ7
UniRef90:
UniRef90_Q96QZ7
UniRef50:
UniRef50_Q96QZ7
UniGene:
Hs.476636
CCDS:
CCDS2904.1,
CCDS33781.1,
CCDS33780.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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