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9221 NOLC1

9221

NOLC1

nucleolar and coiled-body phosphoprotein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition nucleolar and coiled-body phosphoprotein 1

研究结论

Date Results Publications
2020-06-20 12:13:00 This study suggests that the dynamic distribution of telomerase between Cajal bodies and nucleoplasm uniquely impacts telomere length maintenance and identifies Nopp140 as a novel player in telomere biology. 31664887
2019-11-30 12:17:00 Nucleolar TRF2 attenuated nucleolus stress-induced hepatocellular carcinoma cell-cycle arrest by altering rRNA synthesis via interaction with NOLC1. 29725012
2019-03-09 11:36:00 Identification and validation of NOLC1 might be a promising therapeutic strategy for the management of multidrug resistance of non-small cell lung cancer patients. 30505321
2017-06-24 13:00:00 In this study, the disordered feature of Nopp140 and the effect of CK2alpha on the structure of Nopp140 were examined using single-molecule fluorescence resonance energy transfer (smFRET) and electron paramagnetic resonance (EPR). 27297113
2016-03-12 10:22:00 D120 and R195 of H5N1 influenza virus NS1 were crucial for the binding to host NOLC1. 25645906

名称对应

Type IDs
Synonymous NOPP130, NOPP140, NS5ATP13, P130
Gene
UniProtKB-ID: NOLC1_HUMAN, B2RAU8_HUMAN, Q96J17_HUMAN
UniprotKB: Q14978, B2RAU8, Q96J17
UniParc: UPI0000366713, UPI0000072B2D, UPI0001750782, UPI000013E575, UPI000006FA6C
EMBL: BC006769, Z34289, AL500527, AY820769, CH471066, BC001883, D21262, AK314363, AK056755
Ensembl: ENSG00000166197
KO: hsa:9221
Nucleutide sequences
EMBL-CDS: EAW49714.1, AAV67777.1, EAW49715.1, CAA84063.1, AAH01883.1, BAA04803.1, BAG36995.1, EAW49718.1, BAG51805.1, EAW49717.1, EAW49713.1, AAH06769.1
Gene_ORFName: hCG_25636
Ensembl_TRS: ENST00000405356, ENST00000488254, ENST00000605788
Protein sequencees
Ensembl_PRO: ENSP00000385410, ENSP00000475080, ENSP00000474710
RefSeq: NP_001271317.1, XP_005270330.1, NP_001271318.1, NP_004732.2
Others
UniRef100: UniRef100_Q14978, UniRef100_B2RAU8, UniRef100_Q96J17
UniRef90: UniRef90_Q14978
UniRef50: UniRef50_Q14978
UniGene: Hs.523238
CCDS: CCDS65925.1, CCDS7530.1, CCDS65926.1

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