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92170 MTG1

92170

MTG1

mitochondrial ribosome associated GTPase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitochondrial ribosome associated GTPase 1

研究结论

Date Results Publications
2020-06-20 11:04:00 dampening oxidative stress with N-acetylcysteine (NAC) lowered hypertrophy in MTG1 KO to WT levels. Collectively, our data indicate that MTG1 protects against pressure overload-induced cardiac hypertrophy and dysfunction by preserving mitochondrial function and reducing oxidative stress and downstream TAK1 stress signaling. 30707992
2019-06-29 11:50:00 MTG1 establishes a quality control checkpoint in mitoribosome assembly. In conclusion, MTG1 controls mitochondrial translation by coupling mtLSU assembly with intersubunit bridge formation using the intrinsic GEF activity acquired by the mtSSU through mS27, a unique occurrence in translational systems. 30085276
2013-06-15 12:03:00 The results suggested that Mtg1 functions with the large subunit of the mitochondrial ribosome, and are involved in both the translation and assembly of respiratory complexes. 23396448
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20877624

名称对应

Type IDs
Synonymous GTP, GTPBP7
Gene
UniProtKB-ID: MTG1_HUMAN
UniprotKB: Q9BT17
UniParc: UPI0000070752, UPI00004588B9
EMBL: BC004409, AL360181, BC026039, AL161645, AK074976, BC000920, BC035721
Ensembl: ENSG00000148824
KO: hsa:92170
Nucleutide sequences
EMBL-CDS: AAH04409.1, BAC11327.1, AAH35721.1, AAH26039.1, AAH00920.1
Ensembl_TRS: ENST00000317502
Protein sequencees
Ensembl_PRO: ENSP00000323047
RefSeq: NP_612393.2
Others
UniRef100: UniRef100_Q9BT17
UniRef90: UniRef90_Q9BT17
UniRef50: UniRef50_Q9BT17
UniGene: Hs.501578
CCDS: CCDS31320.1

全选

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研究热度

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