| Type | Description |
|---|---|
| Definition | VAMP associated protein B and C |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:15:00 | CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy. | 32525583 |
| 2021-01-16 15:59:00 | VAPB ER-Aggregates, A Possible New Biomarker in ALS Pathology. | 31936602 |
| 2020-07-25 10:15:00 | Authors now show by immunoelectron microscopy that VAPB also localizes to the inner nuclear membrane (INM). Using a modified enhanced ascorbate peroxidase 2 (APEX2) approach with rapamycin-dependent targeting of the peroxidase to a protein of interest, we searched for proteins that are in close proximity to VAPB, particularly at the INM. | 31519755 |
| 2020-06-27 10:20:00 | Cells with even partially depleted VAPB showed an increase in Golgi- and acidic vesicle-localized phosphatidylinositol-4-phosphate (PI4P) and reduced neurite extension when induced to differentiate. | 30745341 |
| 2020-06-20 11:07:00 | VAP proteins (VAPs) mediate ER to Golgi tethering and their loss may affect phosphatidylinositol-4-phosphate (PtdIns4P) transfer between these organelles. Loss of VAPs elevates PtdIns4P levels in the Golgi, leading to an expansion of the endosomal pool derived from the Golgi. | 30741620 |
| Type | IDs |
|---|---|
| Synonymous | ALS8, VAMP-B, VAP-B |
| Gene |
UniProtKB-ID:
VAPB_HUMAN,
Q53XM7_HUMAN
UniprotKB:
O95292,
Q53XM7
UniParc:
UPI0000048ED2,
UPI000002B6A0
EMBL:
BT009811,
AF086628,
AF086629,
AK023241,
AL035455,
CH471077,
BC001712,
AY358464,
AF160212
Ensembl:
ENSG00000124164
KO:
hsa:9217
|
| Nucleutide sequences |
EMBL-CDS:
AAD13577.1,
AAF67013.1,
AAD13578.1,
AAH01712.1,
AAQ88829.1,
BAG51174.1,
EAW75494.1,
EAW75495.1,
AAP88813.1
Gene_ORFName:
UNQ484/PRO983,
hCG_26693
Ensembl_TRS:
ENST00000475243,
ENST00000395802
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000417175,
ENSP00000379147
RefSeq:
NP_001182606.1,
NP_004729.1
|
| Others |
UniRef100:
UniRef100_O95292
UniRef90:
UniRef90_O95292
UniRef50:
UniRef50_O95292
UniGene:
Hs.182625
CCDS:
CCDS56198.1,
CCDS33498.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员