| Type | Description |
|---|---|
| Definition | transmembrane protein 88 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:26:00 | Transmembrane protein 88 exerts a tumor-inhibitory role in thyroid cancer through restriction of Wnt/beta-catenin signaling. | 32710906 |
| 2019-02-23 13:33:00 | TMEM88 plays a significant role in TNF-alpha-enhanced cytokine (IL-6 and IL-1beta) secretion of LX-2 cells via regulating JNK/P38 and canonical Wnt/beta-catenin signaling pathway. | 29159713 |
| 2018-06-23 11:43:00 | TMEM88 inhibits the TGF-beta1-stimulated cell proliferation, migration and extracellular matrix expression in keloid fibroblasts. | 28946191 |
| 2017-07-29 11:23:00 | TMEM88, CCL14, and CLEC3B genes were stable and available in predicting the survival and palindromia time of hepatocellular carcinoma. These genes could function as potential prognostic genes contributing to improve patients' outcomes and survival | 28718365 |
| 2017-05-20 14:54:00 | Results support that OC platinum resistance was correlated with TMEM88 overexpression regulated through decreased promoter methylation. Data suggest that TMEM88 functions as an inhibitor of Wnt signaling, contributing to the development of platinum resistance. | 27374141 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TMM88_HUMAN,
I3L2J3_HUMAN
UniprotKB:
Q6PEY1,
I3L2J3
UniParc:
UPI0000197213,
UPI00002008B2
EMBL:
AC104581,
BC057812
Ensembl:
ENSG00000167874
KO:
hsa:92162
|
| Nucleutide sequences |
EMBL-CDS:
AAH57812.1
Ensembl_TRS:
ENST00000301599,
ENST00000574668
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301599,
ENSP00000459725
RefSeq:
NP_001306870.1,
NP_981956.1,
XP_005256913.1
|
| Others |
UniRef100:
UniRef100_Q6PEY1,
UniRef100_I3L2J3
UniRef90:
UniRef90_Q6PEY1,
UniRef90_I3L2J3
UniRef50:
UniRef50_Q6PEY1,
UniRef50_I3L2J3
UniGene:
Hs.389669
CCDS:
CCDS11121.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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