| Type | Description |
|---|---|
| Definition | LARGE xylosyl- and glucuronyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | Clinical significance of LARGE1 in progression of liver cancer and the underlying mechanism. | 33588034 |
| 2020-05-09 10:25:00 | findings demonstrate that a lack of matriglycan on alpha-dystroglycan is a common feature in rhabdomyosarcoma due to the downregulation of LARGE1, and that ectopic expression of LARGE1 can restore matriglycan modifications and the ability of alpha-dystroglycan to function as an extracellular matrix receptor | 31054580 |
| 2017-07-22 11:16:00 | Large1 gene is a target for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma. | 27636103 |
| 2016-04-16 10:16:00 | B4GAT1 is involved in the initiation of the LARGE-dependent repeating disaccharide that is necessary for extracellular matrix protein binding to O-mannosylated alpha-dystroglycan. | 25279697 |
| 2016-04-16 10:16:00 | A glucuronic acid beta1,4-xylose disaccharide synthesized by B4GAT1 acts as an acceptor primer that can be elongated by LARGE with the ligand-binding heteropolysaccharide. | 25279699 |
| Type | IDs |
|---|---|
| Synonymous | LARGE, MDC1D, MDDGA6, MDDGB6 |
| Gene |
UniProtKB-ID:
LARG1_HUMAN,
X5DR28_HUMAN
UniprotKB:
O95461,
X5DR28
UniParc:
UPI000012E200,
UPI00004DEA5A
EMBL:
Z70288,
AL008715,
BC117425,
BC126404,
CH471095,
AL096754,
Z68287,
Z82173,
AB011181,
KJ534877,
Z69943,
CR456510,
Z69042,
AL008630,
AJ007583
Ensembl:
ENSG00000133424
KO:
hsa:9215
|
| Nucleutide sequences |
EMBL-CDS:
BAA25535.3,
CAI18788.1,
CAQ09434.1,
CAI18785.1,
AAI26405.1,
CAI18784.1,
CAG30396.1,
CAQ11002.1,
CAI17950.1,
CAI17890.1,
CAA07571.1,
AAI17426.1,
CAQ08801.1,
CAQ06856.1,
CAI18769.1,
CAI18772.1,
CAQ10763.1,
CAI18754.1,
CAQ09895.1,
CAQ09323.1,
CAQ08281.1,
EAW60042.1,
EAW60041.1,
AHW56517.1
Gene_ORFName:
hCG_1776784
Ensembl_TRS:
ENST00000354992,
ENST00000402320,
ENST00000397394
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385223,
ENSP00000347088,
ENSP00000380549
RefSeq:
NP_001349882.1,
NP_001365559.1,
XP_011528815.1,
NP_001365556.1,
NP_001365554.1,
XP_024308071.1,
NP_001365557.1,
NP_001365560.1,
NP_598397.1,
NP_001349878.1,
XP_024308070.1,
NP_001365555.1,
NP_004728.1,
NP_001365553.1,
NP_001365558.1,
NP_001349880.1
|
| Others |
UniRef100:
UniRef100_O95461
UniRef90:
UniRef90_O95461
UniRef50:
UniRef50_O95461
UniGene:
Hs.474667
CCDS:
CCDS13912.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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