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9211 LGI1

9211

LGI1

leucine rich glioma inactivated 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition leucine rich glioma inactivated 1

研究结论

Date Results Publications
2021-02-27 13:51:00 ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis. 33208158
2020-08-12 11:19:00 data show that the patients' intrathecal B-cell autoimmune response is dominated by LGI1 antibodies and that LGI1 antibodies alone are sufficient to promote neuronal excitability, a basis of seizure generation. 31900946
2019-10-12 11:16:00 Expression of LGI1 is increased in high-grade glioma tumors of patients with epilepsy. 29723732
2019-06-22 10:38:00 Study shows that hippocampal dentate gyrus atrophy predicts pattern separation impairment in patients with LGI1 encephalitis. 30625332
2018-12-22 10:47:00 the LGI1-ADAM22 complex functions as the trans-synaptic machinery for precise synaptic transmission 29670100

名称对应

Type IDs
Synonymous ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Gene
UniProtKB-ID: LGI1_HUMAN, A0A0S2Z4X3_HUMAN, A0A0S2Z4S7_HUMAN, A0A0S2Z5G1_HUMAN, A0A1B0GUD3_HUMAN
UniprotKB: O95970, A0A0S2Z4X3, A0A0S2Z4S7, A0A0S2Z5G1, A0A1B0GUD3
UniParc: UPI00000711E2, UPI0000048F03, UPI0000DFF265, UPI0000D6C060, UPI0007DC584B
EMBL: CH471066, AF055636, AK289706, AY358885, AL157396, KU178471, AF473548, BC022500, AK303956, KU178470, AL358154, KU178468
Ensembl: ENSG00000108231
KO: hsa:9211
Nucleutide sequences
EMBL-CDS: AAC99316.1, BAG64882.1, AAH22500.1, AAM22074.1, AAQ89244.1, EAW50052.1, BAF82395.1, EAW50053.1, ALQ33928.1, ALQ33926.1, ALQ33929.1
Gene_ORFName: UNQ775/PRO1569, hCG_2024350
Ensembl_TRS: ENST00000371418, ENST00000630047, ENST00000371413, ENST00000635953
Protein sequencees
Ensembl_PRO: ENSP00000485917, ENSP00000360467, ENSP00000360472, ENSP00000490058
RefSeq: NP_001295205.1, NP_001295204.1, XP_016872401.1, NP_005088.1, XP_016872400.1
Others
UniRef100: UniRef100_A0A1B0GUD3, UniRef100_A0A0S2Z5G1, UniRef100_A0A0S2Z4X3, UniRef100_O95970
UniRef90: UniRef90_A0A2K5ESC6, UniRef90_O95970, UniRef90_A0A2R8MRG8
UniRef50: UniRef50_O95970, UniRef50_A0A452IQA7
UniGene: Hs.533670
CCDS: CCDS7431.1, CCDS76325.1, CCDS81490.1

全选

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研究热度

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