| Type | Description |
|---|---|
| Definition | CD5 molecule |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:43:00 | diffuse large B-cell lymphoma (DLBCL) patients with DECM showed significantly inferior clinical outcomes compared to the CD5(+), MYC(+) or CD5(-)MYC(-) patients. Combinational therapeutic modalities might be a candidate approach to improve the prognosis of these patients. | 31706988 |
| 2020-06-20 12:42:00 | Two different anti-CD5- chimeric antigen receptors with costimulators 4-1BB and 2B4 (referred to as BB.z-natural killer (NK) cells and 2B4.z-NK, respectively) were constructed. 2B4.z-NK cells exhibited rapid proliferation and higher anti-malignant efficacy in both malignant CD5+ cell lines and primary CD5+ malignant cells in vitro through upregulation of activation markers and cytotoxic granule release. | 31097020 |
| 2020-05-16 11:33:00 | Study of four cases of pleomorphic mantle cell lymphoma with an immunophenotype of CD5(-) cyclin D1(-) SOX11(+) and morphologic features compatible with diffuse large B-cell lymphoma. | 31688139 |
| 2020-05-09 12:14:00 | CD5 was found to promote T cell survival by protecting autoreactive T cell from activation-induced cell death, to promote de novo induction of regulatory T cells in the periphery, to modulate Th17 and Th2 differentiation, and to modulate immune responses by modulating dendritic cell functions. (Review) | 30676652 |
| 2020-03-28 10:50:00 | Patients with CD5- Mantle cell lymphoma have a more favorable prognosis than patients with CD5+ MCL. | 31045891 |
| Type | IDs |
|---|---|
| Synonymous | LEU1, T1 |
| Gene |
UniProtKB-ID:
CD5_HUMAN
UniprotKB:
P06127
UniParc:
UPI000013D472
EMBL:
AJ237928,
X04391,
AK292698,
AJ237930,
AJ237931,
BC027901,
X89405,
EF064752,
AJ237927,
AP000437,
AJ237929,
AJ237932
Ensembl:
ENSG00000110448
KO:
hsa:921
|
| Nucleutide sequences |
EMBL-CDS:
CAA61584.2,
ABK41935.1,
BAF85387.1,
AAH27901.1,
CAA27979.1
Ensembl_TRS:
ENST00000347785
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342681
RefSeq:
NP_001333385.1,
NP_055022.2
|
| Others |
UniRef100:
UniRef100_P06127
UniRef90:
UniRef90_P06127
UniRef50:
UniRef50_P06127
UniGene:
Hs.58685
CCDS:
CCDS8000.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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