| Type | Description |
|---|---|
| Definition | fusion protein |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 10:36:00 | Using both coimmunoprecipitation and flow-cytometric strategies, we found a bidentate interaction between Nipah virus (NiV) G and F, where both the stalk and head regions of NiV G interact with F. This is a new structural-biological finding for the paramyxoviruses. Additionally, our studies disclosed regions of the NiV G and F glycoproteins dispensable for the G and F interactions. | 27654290 |
| 2016-06-11 12:01:00 | Deletions of more than four residues in F protein did not affect F uptake or endosomal cleavage but downregulated the surface expression, likely by delaying the intracellular trafficking through endosomal-recycling compartments. | 26059400 |
| 2015-07-25 11:44:00 | Data suggest that fusion of Nipah viruses with host cells is facilitated by two of viral membrane proteins, G and F proteins; G protein binds to human ephrins B2 and B3; this interaction triggers F protein to mediate virus-host fusion. | 24615845 |
| 2013-11-16 10:04:00 | These findings are consistent with a general mechanism of paramyxovirus fusion activation in which the stalk domain of the receptor binding protein is responsible for F activation. | 23903846 |
| 2013-04-20 12:06:00 | These findings suggest that the G-F interaction is not mediated entirely by the stalk domain of G. | 23283956 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FUS_NIPAV,
A0A1L7B8D7_NIPAV
UniprotKB:
Q9IH63,
A0A1L7B8D7
UniParc:
UPI00000F1857
EMBL:
KY425655,
AJ627196,
AF212302,
AJ564622,
AF238466,
AF376747,
KY425646,
AY029768,
AJ564621,
AY029767,
AJ564623
KO:
vg:920954
|
| Nucleutide sequences |
EMBL-CDS:
AAM13405.1,
CAD92356.1,
CAD92350.1,
AAK50544.1,
CAD92362.1,
AAK29087.1,
CAF25496.1,
AAK50553.1,
AAF73956.1,
APT69700.1,
APT69633.1
|
| Protein sequencees |
RefSeq:
NP_112026.1
|
| Others |
UniRef100:
UniRef100_Q9IH63
UniRef90:
UniRef90_Q9IH63
UniRef50:
UniRef50_Q9IH63
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.proteinEnsembl}} |
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Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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