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919 CD247

919

CD247

CD247 molecule

protein-coding

Homo sapiens

基因描述

Type Description
Definition CD247 molecule

研究结论

Date Results Publications
2020-01-11 12:16:00 CD47 is not modulated at different uveal melanoma stages. 31277366
2020-01-11 10:54:00 expression in peripheral blood lymphocytes from patients with ovarian cancer is decreased compared with ovarian cyst patients; expression in tumor infiltrating lymphocytes with cancer tissue is decreased compared with adjacent tissues 31861005
2019-12-21 11:34:00 We have developed a clinically translatable bispecific antibody that redirects human T cells to safely and effectively treat malignant glioma. On the basis of these results, we have developed a clinical study of hEGFRvIII-CD3 bi-scFv for patients with EGFRvIII-positive malignant glioma. 29703821
2019-07-13 12:25:00 Our study did not show significant association of CD226 and CD247 genetic polymorphisms with the risk of SSc or the presence of clinical manifestations except than FVC. In other words, CD226 and CD247 genetic variants may not contribute to SSc pathogenesis in Iranian population. 29338153
2019-04-13 10:58:00 We conclude that downregulated CD3zeta confers a proinflammatory phenotype to systemic lupus erythematosus NK cells and contributes to their altered function in patients with systemic lupus erythematosus . 29602774

名称对应

Type IDs
Synonymous CD3-ZETA, CD3H, CD3Q, CD3Z, IMD25, T3Z, TCRZ
Gene
UniProtKB-ID: CD3Z_HUMAN
UniprotKB: P20963
UniParc: UPI0000127363, UPI0000127362
EMBL: AL359962, AL031733, CH471067, AK313946, BC025703, DQ072717, J04132
Ensembl: ENSG00000198821
KO: hsa:919
Nucleutide sequences
EMBL-CDS: AAY57330.1, EAW90792.1, BAG36664.1, AAH25703.1, AAA60394.1
Ensembl_TRS: ENST00000392122, ENST00000362089
Protein sequencees
Ensembl_PRO: ENSP00000354782, ENSP00000375969
RefSeq: NP_001365445.1, XP_011508446.1, NP_932170.1, NP_001365444.1, NP_000725.1, XP_011508447.1
Others
UniRef100: UniRef100_P20963
UniRef90: UniRef90_P20963
UniRef50: UniRef50_P20963
UniGene: Hs.156445
CCDS: CCDS1261.1, CCDS1260.1

全选

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