| Type | Description |
|---|---|
| Definition | chordin like 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 10:10:00 | Finally, in vivo experiments confirmed that CHRDL1 acted as a tumor suppressor gene in suppressing tumor growth and metastasis | 28423564 |
| 2017-05-30 11:57:00 | Results show that Chrdl1 expression is upregulated in numerous breast cancer cells following TGF-beta stimulation and demonstrated that Chrdl1 acts as an inhibitor of BMP4-induced migration and invasion. | 26976638 |
| 2017-01-14 10:12:00 | These studies have identified and validated new factors enriched in juvenile chondrocytes as compared to adult chondrocytes including secreted extracellular matrix factors chordin-like 1 (CHRDL1) and microfibrillar-associated protein 4 (MFAP4). | 26955889 |
| 2016-02-27 10:27:00 | We provide the initial confirmation that X-linked megalocornea is associated with mutations in the CHRDL1 gene. | 24073597 |
| 2016-02-20 10:40:00 | CHRDL1 plays a key role in cornea homeostasis as evidenced by disease causing mutations in X-linked megalocornea. | 25712132 |
| Type | IDs |
|---|---|
| Synonymous | CHL, MGC1, MGCN, NRLN1, VOPT, dA141H5.1 |
| Gene |
UniProtKB-ID:
CRDL1_HUMAN
UniprotKB:
Q9BU40
UniParc:
UPI0000367765,
UPI00003D16A9,
UPI00001BBFB2,
UPI00017A74C2
EMBL:
AK293106,
CH471120,
AL591489,
AL049176,
BC002909,
AK297563,
AY608914,
AK312270
Ensembl:
ENSG00000101938
KO:
hsa:91851
|
| Nucleutide sequences |
EMBL-CDS:
AAH02909.2,
AAU25841.1,
BAF85795.1,
EAX02656.1,
BAG59955.1,
EAX02657.1
Ensembl_TRS:
ENST00000482160,
ENST00000372042,
ENST00000444321,
ENST00000394797
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399739,
ENSP00000361112,
ENSP00000378276,
ENSP00000418443
RefSeq:
NP_001354136.1,
NP_660277.2,
NP_001137454.1,
NP_001137455.2,
NP_001354134.1,
NP_001354135.1,
NP_001137453.1,
XP_005262279.1,
NP_001354133.1,
NP_001354138.1,
NP_001354137.1
|
| Others |
UniRef100:
UniRef100_Q9BU40
UniRef90:
UniRef90_Q9BU40
UniRef50:
UniRef50_Q9BU40
UniGene:
Hs.496587
CCDS:
CCDS48149.1,
CCDS48148.2,
CCDS14553.1,
CCDS48150.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA. |
1 |
| 2 |
The Wellcome Trust Sanger Institute |
1 |
| 3 |
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA. |
1 |
| 4 |
National Institute for Basic Biology |
1 |
| 5 |
Helix Research Institute |
1 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Richard A Gibbs |
3 |
| 2 |
Sumio Sugano |
3 |
| 3 |
Yutaka Suzuki |
3 |
| 4 |
Anne Hodgson |
2 |
| 5 |
Kim C Worley |
2 |