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91851 CHRDL1

91851

CHRDL1

chordin like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition chordin like 1

研究结论

Date Results Publications
2017-12-02 10:10:00 Finally, in vivo experiments confirmed that CHRDL1 acted as a tumor suppressor gene in suppressing tumor growth and metastasis 28423564
2017-05-30 11:57:00 Results show that Chrdl1 expression is upregulated in numerous breast cancer cells following TGF-beta stimulation and demonstrated that Chrdl1 acts as an inhibitor of BMP4-induced migration and invasion. 26976638
2017-01-14 10:12:00 These studies have identified and validated new factors enriched in juvenile chondrocytes as compared to adult chondrocytes including secreted extracellular matrix factors chordin-like 1 (CHRDL1) and microfibrillar-associated protein 4 (MFAP4). 26955889
2016-02-27 10:27:00 We provide the initial confirmation that X-linked megalocornea is associated with mutations in the CHRDL1 gene. 24073597
2016-02-20 10:40:00 CHRDL1 plays a key role in cornea homeostasis as evidenced by disease causing mutations in X-linked megalocornea. 25712132

名称对应

Type IDs
Synonymous CHL, MGC1, MGCN, NRLN1, VOPT, dA141H5.1
Gene
UniProtKB-ID: CRDL1_HUMAN
UniprotKB: Q9BU40
UniParc: UPI0000367765, UPI00003D16A9, UPI00001BBFB2, UPI00017A74C2
EMBL: AK293106, CH471120, AL591489, AL049176, BC002909, AK297563, AY608914, AK312270
Ensembl: ENSG00000101938
KO: hsa:91851
Nucleutide sequences
EMBL-CDS: AAH02909.2, AAU25841.1, BAF85795.1, EAX02656.1, BAG59955.1, EAX02657.1
Ensembl_TRS: ENST00000482160, ENST00000372042, ENST00000444321, ENST00000394797
Protein sequencees
Ensembl_PRO: ENSP00000399739, ENSP00000361112, ENSP00000378276, ENSP00000418443
RefSeq: NP_001354136.1, NP_660277.2, NP_001137454.1, NP_001137455.2, NP_001354134.1, NP_001354135.1, NP_001137453.1, XP_005262279.1, NP_001354133.1, NP_001354138.1, NP_001354137.1
Others
UniRef100: UniRef100_Q9BU40
UniRef90: UniRef90_Q9BU40
UniRef50: UniRef50_Q9BU40
UniGene: Hs.496587
CCDS: CCDS48149.1, CCDS48148.2, CCDS14553.1, CCDS48150.1

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