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91833 WDR20

91833

WDR20

WD repeat domain 20

protein-coding

Homo sapiens

基因描述

Type Description
Definition WD repeat domain 20

研究结论

Date Results Publications
2019-03-09 12:51:00 WDR20 plays a crucial role in as a "targeting subunit" that modulates CRM1-dependent shuttling of the USP12/UAF1/WDR20 complex between the plasma membrane, cytoplasm and nucleus. 30466959
2018-12-01 10:22:00 Results identified WDR20 as an important adaptor protein involved in ERAD system by promoting protein ubiquitination. 29655804
2017-08-26 12:16:00 UAF1 and WDR20 interact with USP12 at two distinct sites far from its catalytic center, allosterically activating the enzyme. 27373336
2016-08-27 11:57:00 our data suggest that downregulation of WDR20 due to 14q loss may be involved in the malignant transformation of ccRCCs, in part through activation of the ERK and protein kinase B/AKT pathways 26790128
2010-09-15 22:05:00 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) 20628086

名称对应

Type IDs
Synonymous DMR
Gene
UniProtKB-ID: WDR20_HUMAN, Q5JPH5_HUMAN, A0A088AWN2_HUMAN
UniprotKB: Q8TBZ3, Q5JPH5, A0A088AWN2
UniParc: UPI00016398CC, UPI00004C3DF5, UPI0001637D30, UPI000000CC72, UPI000019C571, UPI000019C572, UPI0004E4CB17, UPI000019C56F, UPI0000E23AC1, UPI000007111A
EMBL: AL133558, AL359402, BC028387, AK297727, KF456012, AF327354, AL832500, CH471061, AL133223, BX248274, BC030654
Ensembl: ENSG00000140153
KO: hsa:91833
Nucleutide sequences
EMBL-CDS: BAG60080.1, AAH30654.1, AAL56014.1, CAD62602.1, CAB63713.1, AAH28387.1, CAI46118.1, EAW81769.1
Gene_ORFName: hCG_24747
Ensembl_TRS: ENST00000454394, ENST00000555879, ENST00000556807, ENST00000556511, ENST00000342702, ENST00000322340, ENST00000299135, ENST00000335263, ENST00000424963
Protein sequencees
Ensembl_PRO: ENSP00000450636, ENSP00000335434, ENSP00000314209, ENSP00000452470, ENSP00000341037, ENSP00000451633, ENSP00000406084, ENSP00000299135, ENSP00000395793
RefSeq: NP_001340609.1, NP_001340589.1, NP_001229343.1, XP_011535641.1, XP_016877274.1, NP_001340593.1, NP_001340610.1, NP_653175.2, NP_001340592.1, NP_001340606.1, XP_011535647.1, XP_011535640.1, XP_006720376.1, XP_011535658.1, NP_001229347.1, NP_001340585.1, XP_016877256.1, XP_016877270.1, XP_011535648.1, NP_001229346.1, XP_011535643.1, XP_011535655.1, XP_011535660.1, NP_001340597.1, NP_001317157.1, XP_011535649.1, NP_001340588.1, NP_001340598.1, XP_011535637.1, XP_011535642.1, XP_006720371.1, NP_001340599.1, NP_001340590.1, XP_011535645.1, NP_001340607.1, NP_851808.1, NP_001340608.1, NP_001340594.1, XP_011535646.1, NP_001340602.1, NP_001340604.1, NP_001307059.1, NP_001229344.1, NP_001229345.1, XP_006720373.1, XP_024305510.1, XP_006720374.1, NP_001340595.1, NP_851825.1, XP_011535638.1, NP_001340586.1, XP_016877261.1, XP_011535654.1, NP_001340596.1, NP_001340591.1, NP_001340587.1, XP_006720372.1, NP_001340605.1, NP_001340603.1, XP_011535639.1, XP_024305511.1, NP_001340601.1, NP_001340600.1, XP_016877263.1
Others
UniRef100: UniRef100_Q5JPH5, UniRef100_Q8TBZ3, UniRef100_A0A088AWN2
UniRef90: UniRef90_A0A2I3MKZ9, UniRef90_Q5JPH5, UniRef90_Q8TBZ3
UniRef50: UniRef50_A0A2I3MKZ9, UniRef50_A0A3L8SVU8, UniRef50_Q8TBZ3
UniGene: Hs.36859
CCDS: CCDS55944.1, CCDS55943.1, CCDS9968.1, CCDS55945.1, CCDS9969.1, CCDS55942.1, CCDS9970.1

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