| Type | Description |
|---|---|
| Definition | Cdk5 and Abl enzyme substrate 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-21 11:45:00 | We have identified four potentially pathogenic missense CABLES1 variants as a novel, although infrequent, cause of Cushing's Disease in children and young adults. | 28533356 |
| 2018-03-17 11:20:00 | miR199a-3p and P53 are coupled through CABLES1 and comprise a novel negative feedback loop that likely contributes to cardiac c-kit(+) cell proliferation and apoptosis. | 28583208 |
| 2017-05-13 20:18:00 | Cables1/p21 pathway has a strong effect on the induction of cell senescence and inhibition of cell growth, and acts as a novel regulatory mechanism in which p21 is probably one of several downstream effector molecules to mediate Cables1. | 28118639 |
| 2016-07-02 11:20:00 | CABLES1 is a critical regulator of corticotrope proliferation that defines a pathway often inactivated in Cushing disease | 26695862 |
| 2015-08-01 10:27:00 | the results suggest Cables1 as a novel p21 regulator through maintaining p21 stability and support the model that the tumor-suppressive function of Cables1 occurs at least in part through enhancing the tumor-suppressive activity of p21. | 24975575 |
| Type | IDs |
|---|---|
| Synonymous | CABL1, CABLES, HsT2563, IK3-1 |
| Gene |
UniProtKB-ID:
CABL1_HUMAN,
A7K6Y5_HUMAN,
A0A024RC20_HUMAN
UniprotKB:
Q8TDN4,
A7K6Y5,
A0A024RC20
UniParc:
UPI00004C2CAA,
UPI0000D6BBB4,
UPI00000732F0,
UPI000006D3A3
EMBL:
AC011731,
EF028204,
AF348525,
AK296407,
BC037218,
BC004124,
AC105247,
CH471088,
AK093243,
EF444961
Ensembl:
ENSG00000134508
KO:
hsa:91768
|
| Nucleutide sequences |
EMBL-CDS:
AAH04124.2,
BAG59072.1,
BAC04107.1,
AAL83906.1,
AAH37218.1,
ABL77400.1,
ACA05957.1,
EAX01148.1,
EAX01147.1
Gene_ORFName:
hCG_37757
Ensembl_TRS:
ENST00000256925,
ENST00000400473,
ENST00000420687
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383321,
ENSP00000413851,
ENSP00000256925
RefSeq:
NP_612384.1,
NP_001094089.1,
NP_001243367.1
|
| Others |
UniRef100:
UniRef100_A0A024RC20,
UniRef100_Q8TDN4
UniRef90:
UniRef90_A0A2I3NCJ4,
UniRef90_Q8TDN4
UniRef50:
UniRef50_Q8TDN4,
UniRef50_F1NSZ8
UniGene:
Hs.11108
CCDS:
CCDS42417.1,
CCDS58615.1,
CCDS42418.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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