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91754 NEK9

91754

NEK9

NIMA related kinase 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition NIMA related kinase 9

研究结论

Date Results Publications
2020-12-19 13:42:00 Decreased Nek9 expression correlates with aggressive behaviour and predicts unfavourable prognosis in breast cancer. 32098687
2020-09-19 16:30:00 NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1. 31857374
2019-06-15 10:17:00 This study supports a role for NEK9 and MAP2K4 in mediating buparlisib resistance and demonstrates the value of unbiased omic analyses in uncovering resistance mechanisms to targeted therapy in Triple-Negative Breast Cancers. 29472518
2019-05-11 11:43:00 Eg5 localization and centrosome separation in prophase depend on the nuclear microtubule-associated protein TPX2, a pool of which localizes to the centrosomes before nuclear envelope breakdown. This localization involves the kinase Nek9, which phosphorylates TPX2 nuclear localization signal preventing its interaction with importin and nuclear import. 29276125
2018-01-20 10:22:00 High expression level of NEK9 is associated with recurrence in glioblastoma. 26956052

名称对应

Type IDs
Synonymous APUG, LCCS10, NC, NERCC, NERCC1
Gene
UniProtKB-ID: NEK9_HUMAN, Q6PKF2_HUMAN
UniprotKB: Q8TD19, Q6PKF2
UniParc: UPI00003534DE, UPI00001FD89B
EMBL: AY048580, AY080896, BC009336, BC001714, BC112101, AC007055, BC093881, AB082526
Ensembl: ENSG00000119638
KO: hsa:91754
Nucleutide sequences
EMBL-CDS: AAH93881.1, AAD31940.1, AAD31939.1, AAD31938.1, BAC02704.1, AAI12102.1, AAH09336.2, AAL05428.1, AAL87410.1, AAD31936.1, AAH01714.1
Ensembl_TRS: ENST00000238616
Protein sequencees
Ensembl_PRO: ENSP00000238616
RefSeq: XP_024305509.1, NP_001316166.1, NP_149107.4, NP_001316167.1, XP_005268266.1
Others
UniRef100: UniRef100_Q8TD19, UniRef100_Q6PKF2
UniRef90: UniRef90_Q8TD19, UniRef90_Q6PKF2
UniRef50: UniRef50_Q6PKF2, UniRef50_Q8TD19
UniGene: Hs.7200
CCDS: CCDS9839.1

全选

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