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91734 IDI2

91734

IDI2

isopentenyl-diphosphate delta isomerase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition isopentenyl-diphosphate delta isomerase 2

研究结论

Date Results Publications
2016-07-30 11:16:00 The present findings suggest that IDI1 and IDI2 may be associated with the production of cholesterol metabolites in neurons, leading to alpha-synuclein aggregation during the process of Lewy body formation. 25950736
2011-01-01 11:34:00 Within the 40-kb region on 10p15.3 subtelomere, which harbours two genes encoding isopentenyl diphosphate isomerase 1 (IDI1) and IDI2, there was found a segmental copy-number gain in a large proportion of sporadic amyotrophic lateral sclerosis patients. 20955688
2010-01-21 00:00:00 Enzyme kinetic analysis; both isozymes IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway; data suggest that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPARalpha 17202134
2010-01-21 00:00:00 IDI2 is expressed at high levels only in skeletal muscle, where it may be involved in the specialized production of isoprenyl diphosphates for the posttranslational modification of proteins. 14629038
2009-12-02 21:41:00 Observational study of gene-disease association. (HuGE Navigator) 16385451

名称对应

Type IDs
Synonymous IPPI2
Gene
UniProtKB-ID: IDI2_HUMAN
UniprotKB: Q9BXS1
UniParc: UPI000012D1EA
EMBL: AK056950, AF271725, AF271729, AF271727, AF291755, AF271726, BC017778, AF271728
Ensembl: ENSG00000148377
KO: hsa:91734
Nucleutide sequences
EMBL-CDS: AAK29358.1, AAK49437.1, AAH17778.1, AAK49436.1, BAB71322.1
Ensembl_TRS: ENST00000277517
Protein sequencees
Ensembl_PRO: ENSP00000277517
RefSeq: NP_150286.1
Others
UniRef100: UniRef100_Q9BXS1
UniRef90: UniRef90_Q9BXS1
UniRef50: UniRef50_Q9BXS1
UniGene: Hs.9270, Hs.591325
CCDS: CCDS7055.1

全选

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研究热度

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