| Type | Description |
|---|---|
| Definition | lysophosphatidic acid receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:11:00 | The positive expression rate of LPA2 and KLF5 were statistical different in gastric adenocarcinoma, GIN, and normal gastric tissue (P<0.05). LPA2 positive expression was associated with tumor invasion depth, Lauren type, vascular invasion, local lymph node metastasis, and clinical stage (P<0.05). | 31235682 |
| 2019-11-30 10:54:00 | It was revealed that LPA may stimulate the expression of Notch1 and Hes family bHLH transcription factor 1, and the phosphorylation of protein kinase B which belongs to the Notch pathway. | 31115486 |
| 2019-09-28 11:29:00 | Investigated the roles of LPA receptors in the regulation of cellular functions during tumor progression in osteosarcoma cell lines. MG63-R7-C cell activities were inhibited by LPA2 knockdown, suggesting that LPA signaling via LPA2 plays an important role in the acquisition of malignant properties during tumor progression in MG-63 cells. | 29859140 |
| 2019-04-20 12:42:00 | Study shows that due to the high LPAR2 and LPAR4 transcript and protein expression in endometriotic ovarian cysts and positive correlations of both these receptors with the PR-B and ERbeta, respectively, those receptors seem to be the most promising predictors of the endometriotic cysts. | 29621954 |
| 2019-01-05 12:35:00 | LPAR2 and LPAR5 regulate cellular functions during tumor progression in fibrosarcoma HT1080 cells. | 30093116 |
| Type | IDs |
|---|---|
| Synonymous | EDG-4, EDG4, LPA-2, LPA2 |
| Gene |
UniProtKB-ID:
LPAR2_HUMAN,
A0A024R7M9_HUMAN
UniprotKB:
Q9HBW0,
A0A024R7M9
UniParc:
UPI0000048FD7
EMBL:
BC025695,
AC002306,
AF197929,
AY322548,
AF233092,
CH471106,
AF011466
Ensembl:
ENSG00000064547
KO:
hsa:9170
|
| Nucleutide sequences |
EMBL-CDS:
AAB61528.1,
AAC27728.1,
AAP84361.1,
AAG28521.1,
AAH25695.1,
AAF43409.1,
EAW84836.1,
EAW84837.1
Gene_ORFName:
hCG_38563
Ensembl_TRS:
ENST00000586703,
ENST00000542587,
ENST00000407877
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000465280,
ENSP00000384665,
ENSP00000443256
RefSeq:
NP_004711.2,
XP_024307542.1,
XP_016882957.1,
XP_016882958.1
|
| Others |
UniRef100:
UniRef100_Q9HBW0
UniRef90:
UniRef90_Q9HBW0
UniRef50:
UniRef50_P61793
UniGene:
Hs.122575
CCDS:
CCDS12407.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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