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917 CD3G

917

CD3G

CD3g molecule

protein-coding

Homo sapiens

基因描述

Type Description
Definition CD3g molecule

研究结论

Date Results Publications
2019-05-25 10:12:00 These data demonstrate that the T-cell repertoire of patients with CD3G mutations is characterized by a molecular signature that may contribute to the increased rate of autoimmunity associated with this condition. 29653965
2017-02-18 10:37:00 CD3 showed a positive correlation with tryptase and microvascular density, while multiple regression analysis efficaciously predicted microvascular density depending on CD3 and tryptase as predictors, supporting a complex interplay between these cells in sustaining tumor angiogenesis in Diffuse large B cell lymphoma patients. 25957593
2016-04-30 10:22:00 The study identifies an important role of the CD3gamma dileucine motif in T-cell development most probably mediated by its fine-tuning of pre-TCR and TCR expression, down-regulation and signaling. 25920998
2016-01-16 12:13:00 HER2/CD3 BsAb efficiently inhibited the growth of breast cancer tissue by activating and inducing the proliferation of tumor tissue infiltrating lymphocytes. 25760691
2015-11-07 10:39:00 The docking site for CD3 subunits on the T Cell receptor beta chain has been identified by solution NMR. 26109064

名称对应

Type IDs
Synonymous CD3-GAMMA, IMD17, T3G
Gene
UniProtKB-ID: CD3G_HUMAN, B0YIY5_HUMAN
UniprotKB: P09693, B0YIY5
UniParc: UPI000012735F
EMBL: BC113830, X06027, X06026, X06031, X06030, AK313966, X06028, CH471065, EF444965, X04145, X06029
Ensembl: ENSG00000160654
KO: hsa:917
Nucleutide sequences
EMBL-CDS: CAA27764.1, CAA29428.1, AAI13831.1, EAW67368.1, BAG36681.1, ACA05963.1
Gene_ORFName: hCG_1646880
Ensembl_TRS: ENST00000532917
Protein sequencees
Ensembl_PRO: ENSP00000431445
RefSeq: XP_005271781.1, XP_006719004.1, NP_000064.1
Others
UniRef100: UniRef100_P09693
UniRef90: UniRef90_P09693
UniRef50: UniRef50_P09693
UniGene: Hs.2259
CCDS: CCDS8395.1

全选

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