| Type | Description |
|---|---|
| Definition | nexilin F-actin binding protein |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:45:00 | In this study, we explored the potential of whole genome sequencing (WGS) and whole transcriptome sequencing (WTS) to find DNA variants in SCD victims with structural normal hearts. We identified 23 candidate variants in regulatory sequences of cardiac genes, including a variant in the promotor region of NEXN, c.-194A>G, that was found to be statistically significantly. | 31392414 |
| 2020-02-29 11:59:00 | Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN. | 30589415 |
| 2019-11-09 12:18:00 | NEXN targeting by actin-controlled coactivators thus amplifies smooth muscle cell differentiation through the actin cytoskeleton, probably via dense bodies and dense bands. | 30158653 |
| 2016-08-13 10:42:00 | NELINinduced phenotypic transformation of human vascular smooth muscle cell was regulated via the RhoA/SRF signaling pathway. | 26458985 |
| 2015-05-30 12:34:00 | NEXN as a novel gene for ASD and its function to inhibit GATA4 established a critical regulation of an F-actin binding protein on a transcription factor in cardiac development | 24866383 |
| Type | IDs |
|---|---|
| Synonymous | CMH20, NELIN |
| Gene |
UniProtKB-ID:
NEXN_HUMAN,
B4DDI0_HUMAN,
D3DQ79_HUMAN
UniprotKB:
Q0ZGT2,
B4DDI0,
D3DQ79
UniParc:
UPI00017A6CF8,
UPI0000EE313C,
UPI000022ABDC,
UPI00015B3BD8,
UPI00017A7862,
UPI0000EE313B
EMBL:
AK298565,
AC138392,
BC017827,
BC114444,
CH471059,
BC055084,
AK057954,
AF114264,
AC096948,
BC114445,
BC111395,
S67069,
DQ464902,
AK293201
Ensembl:
ENSG00000162614
KO:
hsa:91624
|
| Nucleutide sequences |
EMBL-CDS:
AAH17827.1,
AAI14445.1,
ABE97925.1,
BAB71622.1,
AAD29607.1,
AAB28815.1,
AAI14446.1,
BAG60759.1,
AAH55084.1,
AAI11396.1,
BAG56741.1,
EAX06362.1,
EAX06360.1
Gene_ORFName:
hCG_24063
Ensembl_TRS:
ENST00000330010,
ENST00000334785
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327363,
ENSP00000333938
RefSeq:
XP_005271381.1,
XP_005271380.1,
NP_653174.3,
XP_005271383.1,
XP_005271382.1,
XP_005271379.1,
XP_005271384.1,
NP_001165780.1
|
| Others |
UniRef100:
UniRef100_D3DQ79,
UniRef100_Q0ZGT2
UniRef90:
UniRef90_Q0ZGT2
UniRef50:
UniRef50_Q0ZGT2
UniGene:
Hs.612385
CCDS:
CCDS41351.1,
CCDS53335.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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