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91607 SLFN11

91607

SLFN11

schlafen family member 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition schlafen family member 11

研究结论

Date Results Publications
2021-04-13 10:08:00 Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress. 32209474
2021-04-13 10:07:00 SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy. 32127465
2021-04-03 13:29:00 Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seq. 32474729
2021-02-20 13:29:00 SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway. 32292519
2020-05-30 12:54:00 Depletion of Schlafen 11 (Slfn11) increases the replication of (+)ssRNA viruses from the Flavivirus genus but has no significant effect on the replication of the (-)ssRNA viruses. Quantification of the ratio of genome-containing viral particles to indicates that Slfn11 impairs West Nile virus (WNV) infectivity. Slfn11 prevents WNV-induced downregulation of a subset of tRNAs for the translation of viral polyprotein. 31118262

名称对应

Type IDs
Synonymous SLFN8/9
Gene
UniProtKB-ID: SLN11_HUMAN
UniprotKB: Q7Z7L1
UniParc: UPI0000140B0E
EMBL: CH471147, AK074184, AL831964, AC060766, BC052586, AK092241
Ensembl: ENSG00000172716
KO: hsa:91607
Nucleutide sequences
EMBL-CDS: CAD38606.2, BAB85010.1, EAW80156.1, BAC03835.1, AAH52586.1, EAW80158.1, EAW80157.1
Ensembl_TRS: ENST00000308377, ENST00000394566
Protein sequencees
Ensembl_PRO: ENSP00000312402, ENSP00000378067
RefSeq: NP_689483.3, NP_001098060.1, NP_001362940.1, NP_001362938.1, NP_001098058.1, NP_001098057.1, NP_001374092.1, NP_001362939.1, NP_001374088.1, NP_001374090.1, NP_001362937.1, NP_001362936.1, NP_001374091.1, NP_001374089.1, NP_001098059.1, NP_001374087.1
Others
UniRef100: UniRef100_Q7Z7L1
UniRef90: UniRef90_Q7Z7L1
UniRef50: UniRef50_Q5U311
UniGene: Hs.745059
CCDS: CCDS11294.1

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