| Type | Description |
|---|---|
| Definition | CD3e molecule |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | Multiple Signaling Roles of CD3epsilon and Its Application in CAR-T Cell Therapy. | 32730808 |
| 2020-05-02 11:15:00 | Actin polymerization promotes the recruitment of Nck to the TCR, enhancing downstream signaling, such as phosphorylation of CD3epsilon and lymphocyte activation. | 31674657 |
| 2018-05-26 10:11:00 | The ionic CD3-epsilon -Lck interaction controls the phosphorylation level of the T-cell receptor. | 28659468 |
| 2017-12-09 13:33:00 | A novel pathogenic frameshift variant of CD3E gene has been found in two unrelated T-B+ NK+ severe combined immunodeficiency infants from Turkey. | 28597365 |
| 2017-05-27 10:49:00 | the stalk domains of NKp30 and NKp46, another NCR employing CD3zeta for signaling, were not exchangeable without drastic deficiencies in folding, plasma membrane targeting, and/or ligand-induced receptor signaling. | 27754869 |
| Type | IDs |
|---|---|
| Synonymous | IMD18, T3E, TCRE |
| Gene |
UniProtKB-ID:
CD3E_HUMAN
UniprotKB:
P07766
UniParc:
UPI000012735C
EMBL:
M23318,
M23323,
X03884,
M23320,
M23319,
AK292612,
M23321,
M23322,
M23317,
BC049847,
L34846,
CH471065
Ensembl:
ENSG00000198851
KO:
hsa:916
|
| Nucleutide sequences |
EMBL-CDS:
EAW67364.1,
BAF85301.1,
AAA52295.1,
AAH49847.1,
CAA27516.1
Ensembl_TRS:
ENST00000361763
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354566
RefSeq:
NP_000724.1
|
| Others |
UniRef100:
UniRef100_P07766
UniRef90:
UniRef90_P07766
UniRef50:
UniRef50_P07766
UniGene:
Hs.3003
CCDS:
CCDS31685.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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