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9149 DYRK1B

9149

DYRK1B

dual specificity tyrosine phosphorylation regulated kinase 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition dual specificity tyrosine phosphorylation regulated kinase 1B

研究结论

Date Results Publications
2020-09-19 16:27:00 Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin. 32611815
2020-08-29 12:49:00 Proline Hydroxylation Primes for Autophosphorylation and Activation. 32640193
2019-09-21 12:24:00 Human cytomegalovirus(HCMV) modulates cellular dual specificity tyrosine phosphorylation regulated kinase 1B (DYRK1B) during placental replication which may have implications for congenital HCMV pathogenesis and represent promising antiviral targets. 30501876
2019-04-27 10:56:00 DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B 30496304
2019-03-09 11:01:00 DYRK1B mutations associated with metabolic syndrome interfere with the maturation of DYRK1B by tyrosine autophosphorylation and compromise the conformational stability of the catalytic domain, which renders the kinase susceptible to misfolding. 28743892

名称对应

Type IDs
Synonymous AOMS3, MIRK
Gene
UniProtKB-ID: DYR1B_HUMAN, A0A024R0I0_HUMAN, A0A024R0J6_HUMAN, A0A024R0M8_HUMAN
UniprotKB: Q9Y463, A0A024R0I0, A0A024R0J6, A0A024R0M8
UniParc: UPI0000001059, UPI000002A87F, UPI000002A880
EMBL: Y17999, CH471126, BC025291, AC005393, BC018751, AF205861
Ensembl: ENSG00000281320, ENSG00000105204
KO: hsa:9149
Nucleutide sequences
EMBL-CDS: CAA76990.1, AAH18751.1, AAF15893.1, CAA76991.1, AAC28914.1, CAA76989.1, AAH25291.1, EAW56916.1, EAW56917.1, EAW56921.1, EAW56919.1, EAW56923.1, EAW56922.1
Gene_ORFName: hCG_43347, hCG_43347, hCG_43347
Ensembl_TRS: ENST00000625438, ENST00000625757, ENST00000348817, ENST00000627034, ENST00000323039, ENST00000631090, ENST00000593685, ENST00000625388, ENST00000597639, ENST00000430012
Protein sequencees
Ensembl_PRO: ENSP00000472941, ENSP00000486839, ENSP00000221803, ENSP00000485915, ENSP00000486377, ENSP00000312789, ENSP00000403182, ENSP00000487539, ENSP00000487313, ENSP00000469863
RefSeq: NP_004705.1, NP_006475.1, XP_005259455.1, NP_006474.1
Others
UniRef100: UniRef100_A0A024R0M8, UniRef100_A0A024R0J6, UniRef100_Q9Y463
UniRef90: UniRef90_Q9Z188-2, UniRef90_Q9Y463, UniRef90_A0A0G2KAP6
UniRef50: UniRef50_Q9Y463
UniGene: Hs.130988
CCDS: CCDS12543.1, CCDS46075.1, CCDS12544.1

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