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91464 ISX

91464

ISX

intestine specific homeobox

protein-coding

Homo sapiens

基因描述

Type Description
Definition intestine specific homeobox

研究结论

Date Results Publications
2018-01-13 13:32:00 our results indicate that E2F1 is an important downstream gene of ISX in hepatoma progression. 27175585
2017-10-07 10:09:00 Results show that ISX expression mediated AHR-induced tumorigenesis in hepatocellular carcinoma. 28398627
2017-09-30 11:52:00 Overall, our results identified a feed-forward mechanism of immune suppression in hepatocellular carcinoma organized by ISX, which involves kynurenine-AHR signaling and PD-L1, offering insights into immune escape by hepatocellular carcinoma 28625979
2017-07-15 11:04:00 ISX expression induced by H. pylori infection may lead to intestinal metaplasia and hyperproliferation of gastric mucosa through CDX1/2 and cyclinD1 expression, contributing to gastric carcinogenesis. 26872890
2013-06-01 12:02:00 Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX 23393141

名称对应

Type IDs
Synonymous Pix-1, RAXLX
Gene
UniProtKB-ID: ISX_HUMAN
UniprotKB: Q2M1V0
UniParc: UPI00001BE8E5
EMBL: Z83853, CR749372, BC113633, AL024494, BC112212
Ensembl: ENSG00000175329
KO: hsa:91464
Nucleutide sequences
EMBL-CDS: AAI13634.1, AAI12213.1, CAH18225.1
Ensembl_TRS: ENST00000404699, ENST00000308700
Protein sequencees
Ensembl_PRO: ENSP00000311492, ENSP00000386037
RefSeq: NP_001290437.1
Others
UniRef100: UniRef100_Q2M1V0
UniRef90: UniRef90_Q2M1V0
UniRef50: UniRef50_Q2M1V0
UniGene: Hs.567637
CCDS: CCDS33640.1

全选

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研究热度

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