Type | Description |
---|---|
Definition | ring finger protein 185 |
Date | Results | Publications |
---|---|---|
2018-07-14 11:43:00 | increased RNF185 expression facilitated GC cell migration in vitro and promoted GC metastasis in vivo by downregulating JWA expression. | 29481911 |
2017-08-05 11:11:00 | this study uncovers RNF185 as the first E3 ubiquitin ligase of cyclic GMP-AMP synthase (cGAS), shedding light on the regulation of cGAS activity in innate immune responses | 28273161 |
2014-08-09 12:13:00 | these results indicate that RNF185 negatively regulates osteogenesis through the degradation of Dvl2 and down-regulation of canonical Wnt signaling pathway and suggest a possible therapeutic target in osteoporosis. | 24727453 |
2014-01-04 13:10:00 | data thus identify RNF185 and RNF5 as a novel E3 ligase module that is central to the control of CFTR degradation. | 24019521 |
2012-02-04 10:31:00 | Human BNIP1 colocalizes with RNF185 at mitochondria and is polyubiquitinated by RNF185 through K63-based ubiquitin linkage in vivo. | 21931693 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
RN185_HUMAN,
A0A024R1H4_HUMAN,
A0A024R1F5_HUMAN
UniprotKB:
Q96GF1,
A0A024R1H4,
A0A024R1F5
UniParc:
UPI0000036022,
UPI000006DB28
EMBL:
BC026040,
BC012817,
AK095947,
CR456349,
AC002073,
AK291236,
BC035684,
CH471095,
DQ296561,
DQ296565,
BC009504,
DQ296562,
AC005005,
DQ296559,
BC033166
Ensembl:
ENSG00000138942
KO:
hsa:91445
|
Nucleutide sequences |
EMBL-CDS:
BAC04659.1,
BAF83925.1,
EAW59949.1,
AAH09504.1,
AAH12817.1,
AAH26040.1,
EAW59947.1,
AAH33166.1,
AAH35684.1,
ABB97509.1,
ABB97508.1,
ABB97506.1,
CAG30235.1,
ABB97512.1,
EAW59950.1,
EAW59951.1
Gene_ORFName:
hCG_2010785,
hCG_2010785
Ensembl_TRS:
ENST00000266252,
ENST00000326132,
ENST00000518626
|
Protein sequencees |
Ensembl_PRO:
ENSP00000427755,
ENSP00000266252,
ENSP00000320508
RefSeq:
NP_001129297.1,
NP_689480.2
|
Others |
UniRef100:
UniRef100_Q96GF1,
UniRef100_A0A024R1H4
UniRef90:
UniRef90_Q96GF1,
UniRef90_W5PIT1
UniRef50:
UniRef50_W5PIT1,
UniRef50_Q96GF1
UniGene:
Hs.517553
CCDS:
CCDS13890.1,
CCDS46689.1
|
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