| Type | Description |
|---|---|
| Definition | FA core complex associated protein 24 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 12:06:00 | This is the first report of an FAAP24 loss of function mutation found in human patients with EBV-associated lymphoproliferation. | 27473539 |
| 2014-04-26 10:05:00 | These results demonstrate dual roles of FAAP24 in DNA damage response against crosslinking lesions, one through the formation of FANCM/FAAP24 heterodimer and the other via its ssDNA-binding activity required in optimized checkpoint activation. | 23999858 |
| 2014-03-29 11:15:00 | Crystal structure of the FANCM-FAAP24 complex. | 23932590 |
| 2014-02-15 12:34:00 | Results show that the first HhH motif of FAAP24 is a potential binding site for DNA, which plays a critical role in targeting FANCM-FAAP24 to chromatin. | 24003026 |
| 2013-05-04 11:43:00 | FANCM and FAAP24 play multiple, while not fully epistatic, roles in maintaining genomic integrity. | 23333308 |
| Type | IDs |
|---|---|
| Synonymous | C19orf40 |
| Gene |
UniProtKB-ID:
FAP24_HUMAN,
A0A0S2Z5V6_HUMAN,
K7EKQ4_HUMAN
UniprotKB:
Q9BTP7,
A0A0S2Z5V6,
K7EKQ4
UniParc:
UPI000007380F,
UPI0000202034
EMBL:
BC003535,
AC011449,
KU178830,
BC020247,
BC010170,
AK128668
Ensembl:
ENSG00000131944
KO:
hsa:91442
|
| Nucleutide sequences |
EMBL-CDS:
AAH20247.1,
AAH10170.2,
BAG54708.1,
AAH03535.2,
ALQ34288.1
Ensembl_TRS:
ENST00000588258,
ENST00000590281,
ENST00000589646,
ENST00000590179
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000466121,
ENSP00000468475,
ENSP00000465569,
ENSP00000465728
RefSeq:
NP_689479.1,
NP_001287907.1,
XP_005259450.1
|
| Others |
UniRef100:
UniRef100_Q9BTP7
UniRef90:
UniRef90_Q9BTP7
UniRef50:
UniRef50_Q9BTP7
UniGene:
Hs.579899
CCDS:
CCDS12426.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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