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9135 RABEP1

9135

RABEP1

rabaptin, RAB GTPase binding effector protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition rabaptin, RAB GTPase binding effector protein 1

研究结论

Date Results Publications
2017-10-07 11:11:00 SH2B1 and RABEP1 genetic variants are associated with worsening of LDL and glucose parameters in patients treated with psychotropic drugs 28694205
2016-10-01 10:10:00 The results contradict the model of feedback activation of Rab5 and instead indicate that Rbpt5 is recruited by both Rabex5 recognizing ubiquitylated cargo and by Rab4 to activate Rab5 in a feed-forward manner. 26430212
2016-09-10 11:32:00 ITSN2L interacts with RABEP1 and stimulates its degradation in regulation of endocytosis. 26633357
2016-08-13 10:51:00 The pleckstrin homology domain (PH) of PLD1 itself promotes degradation of HIF-1alpha, then accelerates EGFR endocytosis via upregulation of rabaptin-5 and suppresses tumor progression. 26680696
2015-08-01 11:01:00 analysis of Rabex-5 GEF activation by Rabaptin-5 24957337

名称对应

Type IDs
Synonymous RAB5EP, RABPT5
Gene
UniProtKB-ID: RABE1_HUMAN, B4DMM4_HUMAN
UniprotKB: Q15276, B4DMM4
UniParc: UPI00017A748A, UPI000013FA9E, UPI00000745A5
EMBL: BC041700, AK297535, AF098638, X91141, AK314183
Ensembl: ENSG00000029725
KO: hsa:9135
Nucleutide sequences
EMBL-CDS: AAH41700.1, BAG36864.1, CAA62580.1, AAC70781.1, BAG59936.1
Ensembl_TRS: ENST00000537505, ENST00000341923
Protein sequencees
Ensembl_PRO: ENSP00000339569, ENSP00000445408
RefSeq: XP_016880784.1, NP_001278511.1, XP_011522362.1, NP_004694.2, XP_016880783.1, NP_001077054.1, NP_001278510.1
Others
UniRef100: UniRef100_Q15276, UniRef100_B4DMM4
UniRef90: UniRef90_Q15276
UniRef50: UniRef50_Q15276
UniGene: Hs.592121
CCDS: CCDS45592.1, CCDS42243.1

全选

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