| Type | Description |
|---|---|
| Definition | Shiga toxin 2 subunit A |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 15:01:00 | A single proteolytic cleavage in the Stx2a A-subunit, resulting into two fragments (A1 and A2) linked by a disulfide bridge (cleaved Stx2a), dictates different binding abilities. | 30578712 |
| 2019-09-14 11:45:00 | Shiga toxin 2 subunit A (Stx) translocation across the T84 colon carcinoma cells monolayer is lower in less virulent seropathotype (SPT) group of Stx-producing Escherichia coli strains (STEC) . Stx penetration occurs via a transcellular pathway independently from bacterial type III secretion and attaching and effacing lesion formation. Stx transcytosis across the gut epithelium indicates STEC pathogenicity for humans. | 29533744 |
| 2019-02-16 11:06:00 | The presence of stx2 in stool could be used as risk predictor at an early stage. Shiga toxin-producing Escherichia coli isolates with stx2 toxin and intimin protein were significantly associated with bloody diarrhea. | 29765909 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q7DI68_ECO57
UniprotKB:
Q7DI68
UniParc:
UPI0000000287
EMBL:
CP038428,
SEKQ01000005,
CP038351,
CP038405,
AB048836,
CP038321,
CP038353,
BA000007,
AB048837,
CP038408,
CP038324,
CP038416,
CP038372,
CP038346,
CP038363,
CP038349,
CP038380,
CP038342,
CP038366,
CP038412,
CP038313,
CP038360,
CP038339,
CP038357
EnsemblGenome:
Z1464
KO:
ecs:ECs1205,
ece:Z1464
|
| Nucleutide sequences |
EMBL-CDS:
QKA46925.1,
QKA79136.1,
QJZ89603.1,
BAB34628.1,
BAB33306.1,
QKB74300.1,
QKA31065.1,
NEV30552.1,
QKA38211.1,
QKA54150.1,
QKA05437.1,
QKA89750.1,
QKA75602.1,
QKB65232.1,
QKB58760.1,
QKB54782.1,
QKB17091.1,
BAB33308.1,
QKA58015.1,
QKA10930.1,
QKA86226.1,
QKC00660.1,
QKA63062.1,
QKB02471.1
Gene_ORFName:
E3161_19060,
E4U77_07915,
EVY27_08270,
E3173_17555,
E3153_18140,
E3149_05385,
E4U81_07860,
E4U74_18105,
E4U70_18180,
E4U80_18420,
E3170_10240,
E3168_18105,
E4U69_10035,
E4U90_07940,
E3164_07970,
E4U67_07870,
E3163_18150,
E3172_17095,
E3169_10540,
E4U72_07905,
E4U62_17660,
ECs_1205
|
| Protein sequencees |
RefSeq:
NP_309232.1
|
| Others |
UniRef100:
UniRef100_P09385
UniRef90:
UniRef90_P09385
UniRef50:
UniRef50_P09385
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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