| Type | Description |
|---|---|
| Definition | biorientation of chromosomes in cell division 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-30 12:34:00 | Kinetochore targeting of Bod1 depends on Ndc80 and not PP2A-B56. Bod1 depletion functionally affects Ndc80 phosphorylation at S55. | 29142109 |
| 2018-02-03 11:08:00 | these results suggest that radiation alters miR-142-3p and Bod1 expression in carcinoma cells, and thus contributes to early stages of radiation-induced genomic instability | 27527863 |
| 2017-04-29 12:10:00 | we established two Drosophila models, where neuron-specific knockdown of BOD1 caused pronounced learning deficits and significant abnormalities in synapse morphology. Together our results reveal novel postmitotic functions of BOD1 as well as pathogenic mechanisms that strongly support a causative role of BOD1 deficiency in the aetiology of intellectual disability. | 27166630 |
| 2014-06-14 11:16:00 | Bod1 regulates protein phosphatase 2A at mitotic kinetochores. | 24157919 |
| 2010-01-21 00:00:00 | Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles. | 17938248 |
| Type | IDs |
|---|---|
| Synonymous | FAM44B |
| Gene |
UniProtKB-ID:
BOD1_HUMAN
UniprotKB:
Q96IK1
UniParc:
UPI00001A95AD,
UPI00001A92E5
EMBL:
AK301982,
BC003114,
BC007436,
AY303777,
CH471062
Ensembl:
ENSG00000145919
KO:
hsa:91272
|
| Nucleutide sequences |
EMBL-CDS:
AAP76182.1,
AAH07436.2,
BAG63390.1,
AAH03114.2,
EAW61396.1
Ensembl_TRS:
ENST00000285908,
ENST00000311086
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309644,
ENSP00000285908
RefSeq:
NP_001153123.1,
NP_612378.1,
XP_016865506.1
|
| Others |
UniRef100:
UniRef100_Q96IK1
UniRef90:
UniRef90_Q96IK1
UniRef50:
UniRef50_Q96IK1
UniGene:
Hs.425091
CCDS:
CCDS4389.1,
CCDS54951.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 29142109 |
The Ndc80 complex targets Bod1 to human mitotic kinetochores. Open Biol Katharina Schleicher , Michael Porter , Sara Ten Have , Ramasubramanian Sundaramoorthy , Iain M Porter , Jason R Swedlow |
2017-11-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27527863 |
Radiation induces premature chromatid separation via the miR-142-3p/Bod1 pathway in carcinoma cells. Oncotarget Dong Pan , Yarong Du , Zhenxin Ren , Yaxiong Chen , Xiaoman Li , Jufang Wang , Burong Hu |
2016-09-13 | - |
| 27166630 |
BOD1 Is Required for Cognitive Function in Humans and Drosophila. PLoS Genet Sahar Esmaeeli-Nieh , Michaela Fenckova , Iain M Porter , M Mahdi Motazacker , Bonnie Nijhof , Anna Castells-Nobau , Zoltan Asztalos , Robert WeiÃmann , Farkhondeh Behjati , Andreas Tzschach , Ute Felbor , Harry Scherthan , Seyed Morteza Sayfati , H Hilger Ropers , Kimia Kahrizi , Hossein Najmabadi , Jason R Swedlow , Annette Schenck , Andreas W Kuss |
2016-05-01 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25429064 |
Hum. Mol. Genet. Meian He , Min Xu , Ben Zhang , Jun Liang , Peng Chen , Jong-Young Lee , Todd A Johnson , Huaixing Li , Xiaobo Yang , Juncheng Dai , Liming Liang , Lixuan Gui , Qibin Qi , Jinyan Huang , Yanping Li , Linda S Adair , Tin Aung , Qiuyin Cai , Ching-Yu Cheng , Myeong-Chan Cho , Yoon Shin Cho , Minjie Chu , Bin Cui , Yu-Tang Gao , Min Jin Go , Dongfeng Gu , Weiqiong Gu , Huan Guo , Yongchen Hao , Jie Hong , Zhibin Hu , Yanling Hu , Jianfeng Huang , Joo-Yeon Hwang , Mohammad Kamran Ikram , Guangfu Jin , Dae-Hee Kang , Chiea Chuen Khor , Bong-Jo Kim , Hung Tae Kim , Michiaki Kubo , Jeannette Lee , Juyoung Lee , Nanette R Lee , Ruoying Li , Jun Li , JianJun Liu , Jirong Longe , Wei Lu , Xiangfeng Lu , Xiaoping Miao , Yukinori Okada , Rick Twee-Hee Ong , Gaokun Qiu , Mark Seielstad , Xueling Sim , Huaidong Song , Fumihiko Takeuchi , Toshihiro Tanaka , Phil R Taylor , Laiyuan Wang , Weiqing Wang , Yiqin Wang , Chen Wu , Ying Wu , Yong-Bing Xiang , Ken Yamamoto , Handong Yang , Ming Liao , Mitsuhiro Yokota , Terri Young , Xiaomin Zhang , Norihiro Kato , Qing K Wang , Wei Zheng , Frank B Hu , Dongxin Lin , Hongbing Shen , Yik Ying Teo , Zengnan Mo , Tien Yin Wong , Xu Lin , Karen L Mohlke , Guang Ning , Tatsuhiko Tsunoda , Bok-Ghee Han , Xiao-Ou Shu , E Shyong Tai , Tangchun Wu , Lu Qi |
2015-03-15 |
LOC101927898,
SLC17A2,
CNPY2,
ANAPC10,
FBLN5,
UBD,
FRS2,
ATF7,
NUDT3,
CEP250,
DIS3L2,
CSH1,
ILF3-AS1,
CTBP2,
SLC23A3,
RASGEF1B,
SLC38A9,
CEP120,
CYP19A1,
DDX6,
QSOX2,
PSORS1C1,
ADAMTS17,
ACAN,
DNM2,
DNMT3A,
SDR16C5,
SPAG17,
EXTL3,
DLEU7,
EFEMP1,
ZNF438,
TWISTNB,
GPC5,
KDM6B,
FBXW11,
ATP13A2,
RYBP,
ZBTB38,
LCORL,
DNM3,
GHR,
GHSR,
FAM184B,
ZNF638,
GLI2,
GNA12,
HCG22,
HIST1H2AD,
HMGA1,
C17orf67,
CATSPER3,
IGF1,
IGF1R,
ILF3,
KCNQ1,
LIN28B,
FADS1,
LTBP1,
LTBP2,
MC4R,
MEF2C,
MAP3K3,
MFAP2,
MYC,
NPPC,
SIX6,
PARN,
CRIM1,
DNAJC27,
ATP5G2,
PITX1,
PLAG1,
POLR2B,
ZRANB1,
TET2,
DYM,
DCAF16,
UQCC1,
GSDMC,
ZMIZ1,
ADAMTSL3,
ADGRG6,
PTCH1,
MKL2,
ZFAT,
PTPN9,
PTPN14,
RBBP8,
RBL1,
CCND1,
REST,
PAPPA2,
NCAPG,
HHIP,
NARFL,
HHIP-AS1,
SHOX2,
FNDC3B
|
| 23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
| 24157919 |
Bod1 regulates protein phosphatase 2A at mitotic kinetochores. Nat Commun Iain M Porter , Katharina Schleicher , Michael Porter , Jason R Swedlow |
2013-01-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员