| Type | Description |
|---|---|
| Definition | structural maintenance of chromosomes 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 11:27:00 | SMC3 protein levels impact on karyotype. | 30323357 |
| 2018-10-06 12:10:00 | H2 inhibited lung cancer progression through down-regulating SMC3. | 29852353 |
| 2018-08-11 10:40:00 | Both the SMC1A and SMC3 gene mutation tests were negative in all Chinese patients with Cornelia de Lange syndrome. | 29452578 |
| 2017-06-24 11:24:00 | We identified a large number of mutations in the CC region of both Smc1 and Smc3... we introduced them to the yeast Smc1 and Smc3 CC domains and characterized the effect of these mutant alleles on cohesin's function. We identified a missense mutation in the region of the kink domain of Smc3, which was previously identified in kidney carcinoma | 27307603 |
| 2017-04-15 13:07:00 | Results show that SMC3 is upregulated in asthma patients and suggest that it may play an important role in atopic asthma development, especially in asthma epithelial-mesenchymal transition. | 25515564 |
| Type | IDs |
|---|---|
| Synonymous | BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1 |
| Gene |
UniProtKB-ID:
SMC3_HUMAN
UniprotKB:
Q9UQE7
UniParc:
UPI0000135A8D
EMBL:
AF067163,
AJ005015,
AF020043,
CH471066,
AL359260,
AK289771
Ensembl:
ENSG00000108055
KO:
hsa:9126
|
| Nucleutide sequences |
EMBL-CDS:
EAW49557.1,
AAD32447.1,
BAF82460.1,
CAA06289.1,
AAC14893.1
Ensembl_TRS:
ENST00000361804
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354720
RefSeq:
NP_005436.1
|
| Others |
UniRef100:
UniRef100_Q9UQE7
UniRef90:
UniRef90_Q9UQE7
UniRef50:
UniRef50_Q9UQE7
UniGene:
Hs.24485
CCDS:
CCDS31285.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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