| Type | Description |
|---|---|
| Definition | keratin 75 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-23 11:04:00 | Studies show that mutation in epithelial hair keratin KRT75 leads to a skin condition called pseudofollicularis barbae. Carriers of this mutation have an altered enamel structure and mechanical properties leading to much higher prevalence of caries. [review] | 26709044 |
| 2017-03-04 12:35:00 | The expression of CK5/6 and of P63 suggests a squamous differentiation including in the basaloid thyroid lymphoepithelial complexes | 27130144 |
| 2016-01-16 10:06:00 | CK5/6 have roles in biologically aggressive tumors likely to display resistance to trastuzumab ab initio in women diagnosed with HER2+ cancer | 25742793 |
| 2015-08-29 11:32:00 | There were differences between CK5/6, p63,CK34betaE12 and TTF-1 expression with tumor differentiation in squamous cell carcinoma or adenocarcinomas | 25063315 |
| 2015-07-25 12:04:00 | Analysis of teeth from individuals carrying the KRT75(A161T) variant revealed an altered enamel structure and a marked reduction of enamel hardness, suggesting that a functional keratin network is required for the mechanical stability of tooth enamel. | 25347471 |
| Type | IDs |
|---|---|
| Synonymous | K6HF, KB18, PFB |
| Gene |
UniProtKB-ID:
K2C75_HUMAN
UniprotKB:
O95678
UniParc:
UPI000013CD4E
EMBL:
AK298960,
Y19212,
AC055736,
Y17282
Ensembl:
ENSG00000170454
KO:
hsa:9119
|
| Nucleutide sequences |
EMBL-CDS:
CAA76730.1,
BAG61056.1,
CAB76832.1
Ensembl_TRS:
ENST00000252245
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000252245
RefSeq:
NP_004684.2
|
| Others |
UniRef100:
UniRef100_O95678
UniRef90:
UniRef90_O95678
UniRef50:
UniRef50_O95678
UniGene:
Hs.697046
CCDS:
CCDS8827.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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