| Type | Description |
|---|---|
| Definition | scavenger receptor class F member 2 |
| Date | Results | Publications |
|---|---|---|
| 2015-08-22 11:26:00 | the full VDEGS phenotype may include sclerocornea resulting from homozygosity or compound heterozygosity for loss of function variants in SCARF2. | 24478002 |
| 2010-10-30 10:43:00 | Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. | 20887961 |
| 2010-01-21 00:00:00 | SRECII binds to SRECI and has a similar tissue distribution pattern | 12154095 |
| Type | IDs |
|---|---|
| Synonymous | NSR1, SREC-II, SREC2, SRECRP-1, VDEGS |
| Gene |
UniProtKB-ID:
SREC2_HUMAN
UniprotKB:
Q96GP6
UniParc:
UPI000004D28D,
UPI0000EE7ADB
EMBL:
AF522196,
AB052951,
AB024433,
CH471176,
AC007731,
BC000584,
BC009326
Ensembl:
ENSG00000244486
KO:
hsa:91179
|
| Nucleutide sequences |
EMBL-CDS:
AAH00584.2,
AAH09326.2,
AAN45861.1,
BAD93345.1,
BAC53753.1,
EAX02965.1
Ensembl_TRS:
ENST00000623402,
ENST00000622235
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000477564,
ENSP00000485276
RefSeq:
XP_016884554.1,
NP_699165.3,
NP_878315.2
|
| Others |
UniRef100:
UniRef100_Q96GP6
UniRef90:
UniRef90_Q96GP6
UniRef50:
UniRef50_Q96GP6
UniGene:
Hs.474251
CCDS:
CCDS46666.1,
CCDS13779.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32788342 |
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. Mol Cell Proteomics Molly M Hannigan , Alyson M Hoffman , J Will Thompson , Tianli Zheng , Christopher V Nicchitta |
2020-11-01 | - |
| 31073040 |
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science Jin Huk Choi , Xue Zhong , William McAlpine , Tzu-Chieh Liao , Duanwu Zhang , Beibei Fang , Jamie Russell , Sara Ludwig , Evan Nair-Gill , Zhao Zhang , Kuan-Wen Wang , Takuma Misawa , Xiaoming Zhan , Mihwa Choi , Tao Wang , Xiaohong Li , Miao Tang , Qihua Sun , Liyang Yu , Anne R Murray , Eva Marie Y Moresco , Bruce Beutler |
2019-05-10 | - |
| 30639242 |
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Mol. Cell Joanna R Kovalski , Aparna Bhaduri , Ashley M Zehnder , Poornima H Neela , Yonglu Che , Glenn G Wozniak , Paul A Khavari |
2019-02-21 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 24478002 |
Sclerocornea in a patient with van den Ende-Gupta syndrome homozygous for a SCARF2 microdeletion. Am J Med Genet A Michele P Migliavacca , Nara L M Sobreira , Graziela P M Antonialli , Mariana M Oliveira , Maria Isabel S A Melaragno , Ingele Casteels , Thomy de Ravel , Decio Brunoni , David Valle , Ana Beatriz A Perez |
2014-05-01 | - |
| 21423176 |
Nat. Cell Biol. Jean-Cheng Kuo , Xuemei Han , Cheng-Te Hsiao , John R Yates , Clare M Waterman |
2011-04-01 |
Arhgef7,
CDH2,
PDCD6IP,
ARPC5,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
ARPC2,
CDH13,
G3BP1,
SORBS3,
FLOT1,
ADAM10,
PAK4,
CAP1,
HYOU1,
PROCR,
GNA13,
CFL1,
NCKAP1,
TSPAN9,
RAB10,
YWHAQ,
FERMT2,
TRIOBP,
CDC42EP1,
PACSIN2,
CHP1,
ADD1,
CLTC,
CNN1,
CNN2,
CNN3,
FBLN7,
LAYN,
CSPG4,
CSRP1,
CSRP2,
CTNNA1,
CTNNB1,
DAB2,
DAG1,
SYNPO2,
DNM2,
DPP4,
EFNB2,
EGFR,
EPHA2,
CTTN,
ENG,
EPB41L2,
ALCAM,
FAP,
FAT1,
FHL1,
FHL2,
FHL3,
RRAS2,
ITGA11,
RAB21,
PALLD,
NFASC,
FLNA,
MPRIP,
FLNB,
FLNC,
CYFIP1,
FLOT2,
FLT1,
TNS2,
NCSTN,
RPL13A,
CORO1C,
FLRT2,
FZD2,
TES,
GDI2,
GJA1,
PABPC1,
GNA12,
GNB2,
GIT1,
PDIA3,
GSN,
ANXA1,
ANXA5,
EHD3,
ANXA6,
HMGA1,
HNRNPK,
HSPA1A,
HSPA1B,
HSPA5,
HSPA8,
HSPA9,
HSPB1,
HSPG2,
TNC
|
| 20887961 |
Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. Am. J. Hum. Genet. Natascia Anastasio , Tawfeg Ben-Omran , Ahmad Teebi , Kevin C H Ha , Emilie Lalonde , Rehab Ali , Mariam Almureikhi , Vazken M Der Kaloustian , Junhui Liu , David S Rosenblatt , Jacek Majewski , Loydie A Jerome-Majewska |
2010-10-08 | - |
| 17474147 |
Proteomics Chenggang Wu , Mike Haiting Ma , Kevin R Brown , Matt Geisler , Lei Li , Eve Tzeng , Christina Y H Jia , Igor Jurisica , Shawn S-C Li |
2007-06-01 |
HDAC6,
HCN4,
CHAF1A,
CDH11,
PRG4,
HNRNPR,
SF3B4,
EFS,
TRAIP,
SEC24B,
RPP38,
CENPA,
TGOLN2,
CELF2,
PNMA2,
ZNF274,
EHMT2,
FASTK,
BAZ2A,
MAP4K5,
MAP4K1,
AKAP2,
NXPH3,
GPR45,
CSMD2,
OSBPL5,
CNTFR,
UHMK1,
DUSP15,
ALS2CR12,
CRK,
CRYBB3,
CSF2RA,
DAB2,
DAG1,
DARS,
GSX2,
ASXL1,
DLG4,
DLX4,
DNM1,
AGER,
DNASE1L2,
DNM2,
DOCK1,
DOCK3,
ABAT,
DTX1,
ECT2,
EFNA5,
CELSR3,
CELSR2,
AHSG,
ELK3,
EPS15,
EXTL1,
EXTL3,
F2RL2,
FANCA,
FCGR2B,
DLGAP4,
CD93,
SHANK2,
FOXF2,
TPX2,
RIMS1,
SPEN,
FOXJ1,
TNIK,
CUL9,
NFASC,
EPB41L3,
FLNA,
FLNB,
FLNC,
VPS13A,
SASH1,
AFF2,
ADNP,
BRD4,
TGDS,
CD2AP,
NR5A1,
ABL1,
FYB,
FYN,
GABBR1,
GABRA3,
GAD1,
NELFB,
MYRIP,
DNM3,
OPTC,
HIBCH,
GCDH,
GHR,
NBEA,
RPUSD2,
DKKL1
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员