| Type | Description |
|---|---|
| Definition | regucalcin |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 13:03:00 | Results demonstrate that RGN is epigenetically modified in non-small cell lung cancer (NSCLC) tissues. A high expression of RGN on the RNA level was positively correlated with patients' survival in adenocarcinomas. Also, high expression of Regucalcin seems to be protective in never smokers. | 31718698 |
| 2019-06-29 12:14:00 | In vitro experiments on colonic epithelial cells showed that stable SMP30 expression inhibited but that SMP30 siRNA expression increased TNF-alpha-induced apoptosis. SMP30 inhibition decreased Nrf2 mRNA expression levels (p<0.0001), but SMP30 overexpression increased Nrf2 mRNA expression levels (p=0.0495). | 30266650 |
| 2019-06-23 00:12:00 | SMP-30 overexpression plays a protective role in UVB-induced apoptosis via regulating the expression of apoptosis-related proteins and inhibiting the production of in HLE-B3 cells | 29141388 |
| 2019-03-16 11:04:00 | Data obtained demonstrated that the prolonged survival of patients with renal cell carcinoma (RCC) was associated with a higher regucalcin gene expression, and that the diminished regucalcin gene expression was accompanied by the poor prognosis of patients with RCC. Further findings suggest that regucalcin plays a suppressive role in the promotion of human RCC. | 30387835 |
| 2018-12-01 11:04:00 | Study suggests that regucalcin plays a crucial role as a suppressor in human colorectal cancer, and that the suppressed expression of the regucalcin gene may predispose patients to the promotion of colorectal cancer. | 29956741 |
| Type | IDs |
|---|---|
| Synonymous | GNL, HEL-S-41, RC, SMP30 |
| Gene |
UniProtKB-ID:
RGN_HUMAN,
V9HWF8_HUMAN
UniprotKB:
Q15493,
V9HWF8
UniParc:
UPI0000135A59,
UPI0000211F0B
EMBL:
BC073173,
D31815,
EU794655,
AL513366,
AK223360,
AB028125,
AK290136,
BC050371,
AB032064
Ensembl:
ENSG00000130988
KO:
hsa:9104
|
| Nucleutide sequences |
EMBL-CDS:
AAH50371.1,
BAD97080.1,
BAA84082.1,
BAA06602.1,
AAH73173.1,
BAF82825.1,
BAA78693.1,
ACJ13709.1
Ensembl_TRS:
ENST00000457380,
ENST00000336169,
ENST00000397180,
ENST00000352078
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253303,
ENSP00000380365,
ENSP00000338400,
ENSP00000406568
RefSeq:
XP_024308245.1,
XP_006724631.1,
NP_690608.1,
NP_004674.1,
XP_006724630.1,
NP_001269777.1,
XP_016885443.1,
NP_001269778.1
|
| Others |
UniRef100:
UniRef100_Q15493
UniRef90:
UniRef90_Q15493
UniRef50:
UniRef50_Q15493
UniGene:
Hs.77854
CCDS:
CCDS75968.1,
CCDS14272.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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