| Type | Description |
|---|---|
| Definition | Fc fragment of IgG receptor IIc (gene/pseudogene) |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 13:00:00 | In a cohort of HIV-1-infected South African controllers (n = 71) and progressors (n = 73), the c.134-96C>T minor allele significantly associated with increased odds of HIV-1 disease progression; these data provide additional evidence towards a role for FCGR2C c.134-96C>T in the context of HIV-1. | 30563969 |
| 2018-02-24 11:35:00 | When higher-affinity genotypes for FCGR2A, FCGR3A, and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 treatment | 27742794 |
| 2017-11-26 01:40:00 | The nonclassical open reading frame in the FCGR2C gene (FCGR2C.nc-ORF) was strongly associated with a decreased alloimmunization risk (odds ratio [OR] 0.26, 95% confidence [CI] 0.11-0.64). | 28899854 |
| 2017-09-09 13:08:00 | Gene copy number variation (CNV) of the PKLR, FCGR2A, FCGR2C, and FCGR3 genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria. | 28605553 |
| 2017-06-24 12:29:00 | FCGR2A and FCGR2C polymorphisms may also contribute to immunocomplexemia present in sarcoidosis. | 26801149 |
| Type | IDs |
|---|---|
| Synonymous | CD32, CD32C, CDW32, FCG2, FCRIIC, IGFR2 |
| Gene |
UniProtKB-ID:
FCG2C_HUMAN
UniprotKB:
P31995
UniParc:
UPI000002A988,
UPI000002A986,
UPI000004A8C5,
UPI000002A987
EMBL:
U90938,
U90941,
U90940,
X17652,
U90939
KO:
hsa:9103
|
| Nucleutide sequences |
EMBL-CDS:
CAA35642.1,
AAC12809.1,
AAC12808.1,
AAC12810.1,
CAA35643.1,
AAC12807.1
|
| Protein sequencees |
RefSeq:
NP_963857.3
|
| Others |
UniRef100:
UniRef100_P31995
UniRef90:
UniRef90_P31995
UniRef50:
UniRef50_P31994
UniGene:
Hs.656750
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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