| Type | Description |
|---|---|
| Definition | formin like 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:40:00 | Results demonstrated that N-myristoylation-dependent phosphorylation in FMNL3 occurs at a single Ser residue at position 174, which is a Ser residue conserved between FMNL2 and FMNL3, corresponding to Ser-171 in FMNL2. | 31751425 |
| 2020-01-11 11:41:00 | FMNL3 suppression reduces filopodial assembly by 90%, and FMNL3 is enriched at >95% of filopodial tips. | 30373894 |
| 2020-01-11 10:42:00 | FMNL3 overexpression is related to the metastasis of tongue squamous cell carcinoma and poor prognosis. | 30955218 |
| 2018-11-17 10:55:00 | Study revealed an essential role for FMNL3 in regulating the RhoC/FAK pathway and actin assembly dynamics, and the subsequent promotion of colorectal carcinoma invasion. | 30228782 |
| 2017-04-08 11:28:00 | FMNL3, the target gene of miR-127, is upregulated and acting as an oncogene in ESCC | 27645894 |
| Type | IDs |
|---|---|
| Synonymous | FHOD3, FRL2, WBP-3, WBP3 |
| Gene |
UniProtKB-ID:
FMNL3_HUMAN
UniprotKB:
Q8IVF7
UniParc:
UPI0000049815,
UPI00001C0F7A,
UPI00001FC1CB
EMBL:
AC020612,
AB095934,
AK128195,
BC159100
Ensembl:
ENSG00000161791
KO:
hsa:91010
|
| Nucleutide sequences |
EMBL-CDS:
BAC23110.2,
BAC87319.1,
AAI59101.1
Ensembl_TRS:
ENST00000335154,
ENST00000352151
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344311,
ENSP00000335655
RefSeq:
XP_011537275.2,
XP_011537271.1,
NP_783863.4,
XP_011537272.1,
XP_011537273.1,
NP_001354764.1,
XP_011537270.1,
NP_944489.2,
XP_011537276.1,
XP_011537274.1
|
| Others |
UniRef100:
UniRef100_Q8IVF7
UniRef90:
UniRef90_Q8IVF7
UniRef50:
UniRef50_Q8IVF7
UniGene:
Hs.179838
CCDS:
CCDS41780.1,
CCDS44874.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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