| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | Ubiquitin-Specific Protease 8 Mutant Corticotrope Adenomas Present Unique Secretory and Molecular Features and Shed Light on the Role of Ubiquitylation on ACTH Processing. | 31280266 |
| 2021-01-09 13:32:00 | Ubiquitin-specific peptidase 8 regulates the trafficking and stability of the human organic anion transporter 1. | 32818533 |
| 2020-10-24 14:04:00 | USP8 Mutations and Regulation in Corticotroph Adenomas. | 32053843 |
| 2020-05-30 13:50:00 | Cell-cycle inhibitor p27 was significantly reduced in USP8 mutated pituitary corticotroph adenomas. In contrast, the chaperone HSP90 was expressed higher, and the phosphorylation of the transcription factor CREB was increased in USP8 mutated adenomas. These findings suggest that these proteins are direct or indirect clients of USP8. | 30844069 |
| 2020-03-21 11:57:00 | USP8 mutations occur in functioning and silent corticotrophinomas. | 31581124 |
| Type | IDs |
|---|---|
| Synonymous | HumORF8, PITA4, SPG59, UBPY |
| Gene |
UniProtKB-ID:
UBP8_HUMAN,
A0A024R5S4_HUMAN,
A8K8N5_HUMAN
UniprotKB:
P40818,
A0A024R5S4,
A8K8N5
UniParc:
UPI00017A75E8,
UPI00015DAA56,
UPI0000030306
EMBL:
AC012170,
D29956,
BC110590,
BC038801,
AK296480,
AK292400,
CH471082,
BX537420,
BC051345
Ensembl:
ENSG00000138592
KO:
hsa:9101
|
| Nucleutide sequences |
EMBL-CDS:
AAH51345.1,
CAD97662.1,
AAH38801.1,
BAG59120.1,
BAA06225.2,
AAI10591.1,
EAW77399.1,
EAW77401.1,
EAW77400.1,
BAF85089.1
Gene_ORFName:
hCG_38748
Ensembl_TRS:
ENST00000425032,
ENST00000307179,
ENST00000396444
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379721,
ENSP00000302239,
ENSP00000412682
RefSeq:
XP_011520495.1,
NP_005145.3,
XP_016878209.1,
XP_016878210.1,
XP_016878208.1,
XP_024305866.1,
XP_016878211.1,
NP_001122082.1,
XP_016878207.1,
NP_001269978.1,
XP_006720824.1,
XP_006720825.1
|
| Others |
UniRef100:
UniRef100_P40818,
UniRef100_A8K8N5
UniRef90:
UniRef90_P40818
UniRef50:
UniRef50_P40818
UniGene:
Hs.443731
CCDS:
CCDS10137.1,
CCDS61632.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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