| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:21:00 | USP2-mediated Twist/Bmi1 pathway represents a cell-intrinsic mechanism crucial for CSC regulation besides EMT and provides pre-clinical evidence that targeting USP2 is indeed a promising approach for anti-CSC therapy. | 30918246 |
| 2019-06-22 12:06:00 | These findings have characterized an essential role of USP2a as a potential target for treatment of metastatic cancers. | 29490279 |
| 2019-01-12 11:19:00 | Data suggest that ubiquitin (Ub) and neural precursor cell expressed developmentally down-regulated 8 (NEDD8) residues 4, 12, 14, and 72 serve as the molecular determinants for specific recognition by ubiquitin specific protease 2 protein (USP2). | 28536428 |
| 2018-08-04 11:20:00 | In general, we collect and summarize the factors involved in the alternative splicing of USP2 in this review to further understand the mechanism behind the USP2's alternative splicing | 29230097 |
| 2018-03-17 12:02:00 | Authors show here USP2 is expressed in quiescent and activated T-cells and its expression is 50% lower in CTCL cell lines (MyLa2000, SeAx and Hut-78) than in normal T-cells. | 27351221 |
| Type | IDs |
|---|---|
| Synonymous | UBP41, USP9 |
| Gene |
UniProtKB-ID:
UBP2_HUMAN
UniprotKB:
O75604
UniParc:
UPI00001379D8,
UPI000002B679,
UPI000049DD57,
UPI0000074749
EMBL:
EF445044,
AP003396,
BC002854,
BC041366,
BC002955,
AF079564,
AK292255,
CH471065,
AF440755,
AK057225
Ensembl:
ENSG00000036672
KO:
hsa:9099
|
| Nucleutide sequences |
EMBL-CDS:
ACA06096.1,
EAW67486.1,
AAN65363.1,
AAH02955.1,
BAF84944.1,
AAH02854.1,
EAW67484.1,
AAC28392.1,
BAB71388.1,
ACA06097.1,
EAW67485.1,
AAH41366.1
Ensembl_TRS:
ENST00000260187,
ENST00000525735,
ENST00000455332
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000260187,
ENSP00000436952,
ENSP00000407842
RefSeq:
XP_016874028.1,
NP_001230688.1,
XP_005271779.1,
NP_004196.4,
XP_005271778.1,
NP_741994.1
|
| Others |
UniRef100:
UniRef100_O75604
UniRef90:
UniRef90_O75604
UniRef50:
UniRef50_O75604
UniGene:
Hs.524085
CCDS:
CCDS8422.1,
CCDS8423.1,
CCDS58189.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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