| Type | Description |
|---|---|
| Definition | unc-119 lipid binding chaperone |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:34:00 | The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. | 32554467 |
| 2019-11-09 13:05:00 | UNC119 was significantly upregulated and promoted cell growth in hepatic cancer cells and tissues by the Wnt/beta-catenin signal pathway and migration by TGF-beta/EMT signal pathway. Curcumin treatment inhibited cell proliferation, growth, migration, and invasion by inhibition of those pathways. | 31679307 |
| 2019-09-28 11:42:00 | UNC119 was significantly up-regulated in liver cancer cells and tissues. It promoted cell growth and migration through the Wnt/beta-catenin and TGF-beta/EMT signaling pathways, respectively. | 29552782 |
| 2019-08-31 12:32:00 | UNC119 is significantly up-regulated and promoted cell growth and migration in hepatic cancer cells and tissues via Wnt/b-catenin signal pathway and TGF-b/EMT signal pathway | 30610799 |
| 2019-02-02 10:04:00 | UNC119 was significantly up-regulated in liver cancer cells and tissues. It promoted cell growth and migration through the Wnt/beta-catenin and TGF-beta/EMT signaling pathways, respectively | 29552781 |
| Type | IDs |
|---|---|
| Synonymous | HRG4, IMD13, POC7, POC7A |
| Gene |
UniProtKB-ID:
U119A_HUMAN,
K7EN86_HUMAN
UniprotKB:
Q13432,
K7EN86
UniParc:
UPI000002B66B,
UPI00000012A7,
UPI0000D66D40
EMBL:
AF028788,
AF125997,
AC005726,
BC027176,
AB593014,
AF125998,
U40998,
CH471159,
AF028789,
AK292329
Ensembl:
ENSG00000109103
KO:
hsa:9094
|
| Nucleutide sequences |
EMBL-CDS:
BAF85018.1,
AAD01876.1,
AAD31422.1,
BAJ83969.1,
AAD01875.1,
AAC50360.1,
EAW51095.1,
AAH27176.1,
EAW51098.1,
EAW51094.1
Gene_ORFName:
hCG_31798
Ensembl_TRS:
ENST00000301032,
ENST00000335765,
ENST00000484980
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000337040,
ENSP00000301032,
ENSP00000466831
RefSeq:
XP_011523761.1,
NP_001317095.1,
NP_473376.1,
NP_005139.1
|
| Others |
UniRef100:
UniRef100_K7EN86,
UniRef100_Q13432
UniRef90:
UniRef90_Q13432
UniRef50:
UniRef50_Q13432
UniGene:
Hs.410455
CCDS:
CCDS11233.1,
CCDS11234.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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