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9093 DNAJA3

9093

DNAJA3

DnaJ heat shock protein family (Hsp40) member A3

protein-coding

Homo sapiens

基因描述

Type Description
Definition DnaJ heat shock protein family (Hsp40) member A3

研究结论

Date Results Publications
2020-09-05 13:52:00 Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade. 31081962
2020-07-11 12:46:00 identified and as the HSP70 family proteins that physically interact with DNAJA3, and established their requirement for the phosphorylation of NF-kappaB p65 31005254
2020-06-13 10:24:00 A novel variant of the human mitochondrial DnaJ protein, Tid1, associates with a human disease exhibiting developmental delay and polyneuropathy. 30770860
2019-08-31 13:24:00 Herein, the authors first revealed that Galectin-7 was one of the Tid1-interacting client proteins. An inverse association of protein expression profile between Tid1 and Galectin-7 was determined in head and neck squamous cell carcinoma patients. Low Tid1 and high Galectin-7 expression predicted poor overall survival in head and neck squamous cell carcinoma. 30083263
2016-05-21 12:45:00 Impaired stoichiometry between mtHsp40 and mtHsp70 promotes Opa1L cleavage, leading to cristae opening, decreased OXPHOS, and triggering of mitochondrial fragmentation after reduction in their chaperone function. 25904328

名称对应

Type IDs
Synonymous HCA57, TID1, hTID-1
Gene
UniProtKB-ID: DNJA3_HUMAN, Q59E88_HUMAN, Q53G26_HUMAN, B3KM81_HUMAN
UniprotKB: Q96EY1, Q59E88, Q53G26, B3KM81
UniParc: UPI0001AE680E, UPI0000043C38, UPI0000140FE5, UPI00004F6EAF, UPI000015F315
EMBL: AC012676, CH471112, AK314218, BC032100, AK295391, BC011855, BC014062, AF244136, AF411044, BC007225, BC020248, BC012343, BC030145, AB209923, AK001333, AK223105, AF061749
Ensembl: ENSG00000276726, ENSG00000103423
KO: hsa:9093
Nucleutide sequences
EMBL-CDS: AAF66245.1, AAH11855.1, AAH07225.1, AAH30145.1, AAH32100.1, BAG36892.1, AAH20248.1, AAL35323.1, BAG58345.1, AAH12343.1, AAH14062.1, AAC29066.1, BAD93160.1, BAD96825.1, EAW85305.1, EAW85304.1, BAG50893.1
Gene_ORFName: hCG_15165
Ensembl_TRS: ENST00000431375, ENST00000262375, ENST00000614397, ENST00000612103, ENST00000355296
Protein sequencees
Ensembl_PRO: ENSP00000477570, ENSP00000347445, ENSP00000393970, ENSP00000479815, ENSP00000262375
RefSeq: NP_001128582.1, NP_001273445.1, NP_005138.3
Others
UniRef100: UniRef100_B3KM81, UniRef100_Q96EY1
UniRef90: UniRef90_Q96EY1
UniRef50: UniRef50_Q96EY1
UniGene: Hs.459779
CCDS: CCDS10515.1, CCDS45400.1, CCDS66930.1

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