| Type | Description |
|---|---|
| Definition | spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:58:00 | Patients with clear cell renal carcinoma with high HAF transcript or protein levels showed significantly decreased overall survival compared with those with low HAF. Functional study shows that HAF promotes neurofibromin ubiquitination and degradation independently of oxygen and pVHL, resulting in Ras-ERK pathway activation. | 30705246 |
| 2017-08-05 10:29:00 | SART1 has a role in IFN-mediated anti-Hepatitis B virus response | 28077916 |
| 2016-07-30 11:20:00 | Data indicate that mutant VHL can protect HIF1alpha from SART1-dependent degradation in normoxic conditions, but this protection is lost in hypoxic settings, favoring hypoxia-dependent ccRCC proliferation. | 25915846 |
| 2016-01-30 10:41:00 | SART1 exerts its anti-Hepatitis C virus action through direct transcriptional regulation for some Interferon stimulating genes and alternative splicing for others. | 25481564 |
| 2012-06-30 10:54:00 | This study identifies SART1 as a previously unidentified regulator of c-FLIP and drug-induced activation of caspase-8. | 22027693 |
| Type | IDs |
|---|---|
| Synonymous | Ara1, HAF, HOMS1, SART1259, SNRNP110, Snu66 |
| Gene |
UniProtKB-ID:
SNUT1_HUMAN
UniprotKB:
O43290
UniParc:
UPI00000732D5
EMBL:
BC001058,
AF109680,
AB006198,
BT006637,
AK223016,
AF353625,
AP006287
Ensembl:
ENSG00000175467
KO:
hsa:9092
|
| Nucleutide sequences |
EMBL-CDS:
AAK49523.1,
AAH01058.1,
AAD20223.1,
AAP35283.1,
BAD96736.1,
BAA24056.1
Ensembl_TRS:
ENST00000312397
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310448
RefSeq:
NP_005137.1,
XP_011543647.1,
XP_011543646.1
|
| Others |
UniRef100:
UniRef100_O43290
UniRef90:
UniRef90_O43290
UniRef50:
UniRef50_O43290
UniGene:
Hs.502883
CCDS:
CCDS31611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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