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9088 PKMYT1

9088

PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase, membrane associated tyrosine/threonine 1

研究结论

Date Results Publications
2021-04-03 13:35:00 PKMYT1 aggravates the progression of ovarian cancer by targeting SIRT3. 32495859
2020-09-19 16:29:00 Overexpression of PKMYT1 indicates the poor prognosis and enhances proliferation and tumorigenesis in non-small cell lung cancer via activation of Notch signal pathway. 31173292
2020-05-30 11:42:00 PKMYT1 promoted the growth of prostate cancer cells through targeting CCNB1 and CCNE1 expression. 32234541
2020-05-30 11:33:00 Cancer cells with intrinsic or acquired adavosertib resistance had higher levels of Myt1 compared with sensitive cancer cells. Downregulating Myt1 enhanced ectopic Cdk1 activity and restored sensitivity to adavosertib. Myt1 expression was associated with both a worse disease-free and overall survival in breast cancer patients. 31594837
2020-03-07 11:52:00 Overexpression of PKMYT1 is always found in breast cancer. 31837068

名称对应

Type IDs
Synonymous MYT1, PPP1R126
Gene
UniProtKB-ID: PMYT1_HUMAN, Q0IJ49_HUMAN
UniprotKB: Q99640, Q0IJ49
UniParc: UPI00001FF80D, UPI000004CF52, UPI00001B578B, UPI0000DD4BE2, UPI00001FF80C
EMBL: AK097642, AK301926, AL713779, BC121162, U56816, BC130011, AF549406, AF014118, AC004235, AC004233, BC121161, CH471112, AK098452
Ensembl: ENSG00000127564
KO: hsa:9088
Nucleutide sequences
EMBL-CDS: AAB71843.1, EAW85439.1, AAC04478.1, CAD28540.1, AAC04477.1, EAW85440.1, BAG53500.1, AAN40703.1, AAC50949.1, BAG63346.1, AAI30012.1, AAI21162.1, AAI21163.1
Ensembl_TRS: ENST00000574730, ENST00000573944, ENST00000262300, ENST00000440027, ENST00000574385
Protein sequencees
Ensembl_PRO: ENSP00000460868, ENSP00000397739, ENSP00000458943, ENSP00000459123, ENSP00000262300
RefSeq: NP_872629.1, XP_024306258.1, NP_001245380.1, NP_001245379.1, NP_004194.3, XP_011521036.1, XP_011521038.1, XP_011521037.1
Others
UniRef100: UniRef100_Q99640
UniRef90: UniRef90_Q99640
UniRef50: UniRef50_Q99640
UniGene: Hs.732385
CCDS: CCDS45391.1, CCDS58414.1, CCDS58415.1, CCDS10486.1

全选

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