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90826 PRMT9

90826

PRMT9

protein arginine methyltransferase 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein arginine methyltransferase 9

研究结论

Date Results Publications
2018-06-23 11:18:00 Study demonstrated that PRMT9 is an oncogene that plays an important role in hepatocellular carcinoma cells invasion and metastasis through EMT by regulating Snail expression via activation of the PI3K/Akt/GSK-3beta/Snail signaling pathway. 29603830
2018-03-03 11:18:00 Mechanistically, miR-543 inhibited PRMT9-enhanced cell oxidative phosphorylation, while miR-543 depletion promoted PRMT9-increased HIF-1alpha instability and inhibited glycolysis in osteosarcoma (OS) cells. Clinically, miR-543 expression was negatively correlated with PRMT9 expression in OS tissues. 27911265
2016-05-07 10:43:00 The decrease in PRMT10 was canceled by knockdown of AR or an AR antagonist. These results indicate that PRMT10 plays an important role in androgen-dependent proliferation of prostate cancer cells 25799006
2016-02-13 10:08:00 PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145. 25737013
2015-10-31 10:25:00 Although amino acid substitutions of residues surrounding Arg-508 had no great effect on PRMT9 recognition of SF3B2, moving the arginine residue within this sequence abolished methylation. 25979344

名称对应

Type IDs
Synonymous PRMT10
Gene
UniProtKB-ID: ANM9_HUMAN
UniprotKB: Q6P2P2
UniParc: UPI000004971D, UPI000020B559
EMBL: AK096703, CH471056, BC004337, BC021250, AL137452, BC064403, AC093835, AK128483, AK292904
Ensembl: ENSG00000164169
KO: hsa:90826
Nucleutide sequences
EMBL-CDS: AAH21250.2, BAG53354.1, BAF85593.1, BAC87459.1, AAH04337.1, AAH64403.1, EAX05011.1, EAX05013.1, CAB70744.1
Ensembl_TRS: ENST00000322396
Protein sequencees
Ensembl_PRO: ENSP00000314396
RefSeq: NP_001291387.1, NP_001337071.1, XP_016864314.1, NP_001337073.1, NP_001337070.1, NP_001337072.1, XP_016864312.1, XP_016864313.1, XP_016864315.1, NP_612373.2
Others
UniRef100: UniRef100_Q6P2P2
UniRef90: UniRef90_Q6P2P2
UniRef50: UniRef50_Q6P2P2
UniGene: Hs.591692
CCDS: CCDS3771.1

全选

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